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@ARTICLE{Guidetti:278562,
      author       = {Guidetti, Matteo and Bocci, Tommaso and De Pedro Del
                      Álamo, Marta and Deuschl, Guenther and Fasano, Alfonso and
                      Martinez-Fernandez, Raul and Gasca-Salas, Carmen and Hamani,
                      Clement and Krauss, Joachim K and Kühn, Andrea A and
                      Limousin, Patricia and Little, Simon and Lozano, Andres M
                      and Maiorana, Natale V and Marceglia, Sara and Okun, Michael
                      S and Oliveri, Serena and Ostrem, Jill L and Scelzo, Emma
                      and Schnitzler, Alfons and Starr, Philip A and Temel, Yasin
                      and Timmermann, Lars and Tinkhauser, Gerd and
                      Visser-Vandewalle, Veerle and Volkmann, Jens and Priori,
                      Alberto},
      title        = {{W}ill adaptive deep brain stimulation for {P}arkinson's
                      disease become a real option soon? {A} {D}elphi consensus
                      study.},
      journal      = {npj Parkinson's Disease},
      volume       = {11},
      number       = {1},
      issn         = {2373-8057},
      address      = {[London]},
      publisher    = {Springer Nature},
      reportid     = {DZNE-2025-00595},
      pages        = {110},
      year         = {2025},
      abstract     = {While conventional deep brain stimulation (cDBS) treatment
                      delivers continuous electrical stimuli, new adaptive DBS
                      (aDBS) technology provides dynamic symptom-related
                      stimulation. Research data are promising, and devices are
                      already available, but are we ready for it? We asked leading
                      DBS experts worldwide (n = 21) to discuss a research agenda
                      for aDBS research in the near future to allow full adoption.
                      A 5-point Likert scale questionnaire, along with a Delphi
                      method, was employed. In the next 10 years, aDBS will be
                      clinical routine, but research is needed to define which
                      patients would benefit more from the treatment; second,
                      implantation and programming procedures should be simplified
                      to allow actual generalized adoption; third, new adaptive
                      algorithms, and the integration of aDBS paradigm with new
                      technologies, will improve control of more complex symptoms.
                      Since the next years will be crucial for aDBS
                      implementation, the research should focus on improving
                      precision and making programming procedures more
                      accessible.},
      cin          = {AG Kühn},
      ddc          = {610},
      cid          = {I:(DE-2719)5000008},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40325017},
      pmc          = {pmc:PMC12052990},
      doi          = {10.1038/s41531-025-00974-5},
      url          = {https://pub.dzne.de/record/278562},
}