%0 Journal Article
%A Kuhn, Elizabeth
%A Klinger, Hannah M
%A Amariglio, Rebecca E
%A Wagner, Michael
%A Jessen, Frank
%A Düzel, Emrah
%A Heneka, Michael T
%A Chételat, Gael
%A Rentz, Dorene M
%A Sperling, Reisa A
%A Ebenau, Jarith L
%A Butterbrod, Elke
%A Van Der Flier, Wiesje M
%A Sikkes, Sietske A M
%A Teunnissen, Charlotte E
%A Van Harten, Argonde C
%A Van De Giessen, Elsmarieke M
%A Rami, Lorena
%A Tort, Adria
%A Sánchez Benavides, Gonzalo
%A Gifford, Katherine A
%A Van Hulle, Carol
%A Buckley, Rachel F
%A Biomarkers, Australian Imaging
%T SCD-plus features and AD biomarkers in cognitively unimpaired samples: A meta-analytic approach for nine cohort studies.
%J Alzheimer's and dementia
%V 21
%N 5
%@ 1552-5260
%C Hoboken, NJ
%I Wiley
%M DZNE-2025-00618
%P e14307
%D 2025
%X Specific features of subjective cognitive decline (SCD-plus) have been proposed to indicate an increased risk of preclinical Alzheimer's disease (AD). However, few studies have examined how these features relate to AD biomarkers in cognitively unimpaired (CU) older adults.Meta-analyses were performed using cross-sectional data from nine cohorts (n = 7219, mean age (SD): 71.17 (5.9), 56.5
%K Humans
%K Biomarkers: cerebrospinal fluid
%K Alzheimer Disease: cerebrospinal fluid
%K Alzheimer Disease: diagnosis
%K Alzheimer Disease: diagnostic imaging
%K Cognitive Dysfunction: cerebrospinal fluid
%K Cognitive Dysfunction: diagnosis
%K Amyloid beta-Peptides: cerebrospinal fluid
%K tau Proteins: cerebrospinal fluid
%K Positron-Emission Tomography
%K Female
%K Male
%K Aged
%K Cohort Studies
%K Cross-Sectional Studies
%K Alzheimer's disease (Other)
%K SCD‐Initiative (Other)
%K amyloid pathology (Other)
%K cerebrospinal fluid (Other)
%K meta‐analysis (Other)
%K positron emission tomography (Other)
%K subjective cognitive decline (Other)
%K tau burden (Other)
%K Biomarkers (NLM Chemicals)
%K Amyloid beta-Peptides (NLM Chemicals)
%K tau Proteins (NLM Chemicals)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:39985404
%2 pmc:PMC12079645
%R 10.1002/alz.14307
%U https://pub.dzne.de/record/278782