TY  - JOUR
AU  - Kuhn, Elizabeth
AU  - Klinger, Hannah M
AU  - Amariglio, Rebecca E
AU  - Wagner, Michael
AU  - Jessen, Frank
AU  - Düzel, Emrah
AU  - Heneka, Michael T
AU  - Chételat, Gael
AU  - Rentz, Dorene M
AU  - Sperling, Reisa A
AU  - Ebenau, Jarith L
AU  - Butterbrod, Elke
AU  - Van Der Flier, Wiesje M
AU  - Sikkes, Sietske A M
AU  - Teunnissen, Charlotte E
AU  - Van Harten, Argonde C
AU  - Van De Giessen, Elsmarieke M
AU  - Rami, Lorena
AU  - Tort, Adria
AU  - Sánchez Benavides, Gonzalo
AU  - Gifford, Katherine A
AU  - Van Hulle, Carol
AU  - Buckley, Rachel F
AU  - Biomarkers, Australian Imaging
TI  - SCD-plus features and AD biomarkers in cognitively unimpaired samples: A meta-analytic approach for nine cohort studies.
JO  - Alzheimer's and dementia
VL  - 21
IS  - 5
SN  - 1552-5260
CY  - Hoboken, NJ
PB  - Wiley
M1  - DZNE-2025-00618
SP  - e14307
PY  - 2025
AB  - Specific features of subjective cognitive decline (SCD-plus) have been proposed to indicate an increased risk of preclinical Alzheimer's disease (AD). However, few studies have examined how these features relate to AD biomarkers in cognitively unimpaired (CU) older adults.Meta-analyses were performed using cross-sectional data from nine cohorts (n = 7219, mean age (SD): 71.17 (5.9), 56.5
KW  - Humans
KW  - Biomarkers: cerebrospinal fluid
KW  - Alzheimer Disease: cerebrospinal fluid
KW  - Alzheimer Disease: diagnosis
KW  - Alzheimer Disease: diagnostic imaging
KW  - Cognitive Dysfunction: cerebrospinal fluid
KW  - Cognitive Dysfunction: diagnosis
KW  - Amyloid beta-Peptides: cerebrospinal fluid
KW  - tau Proteins: cerebrospinal fluid
KW  - Positron-Emission Tomography
KW  - Female
KW  - Male
KW  - Aged
KW  - Cohort Studies
KW  - Cross-Sectional Studies
KW  - Alzheimer's disease (Other)
KW  - SCD‐Initiative (Other)
KW  - amyloid pathology (Other)
KW  - cerebrospinal fluid (Other)
KW  - meta‐analysis (Other)
KW  - positron emission tomography (Other)
KW  - subjective cognitive decline (Other)
KW  - tau burden (Other)
KW  - Biomarkers (NLM Chemicals)
KW  - Amyloid beta-Peptides (NLM Chemicals)
KW  - tau Proteins (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:39985404
C2  - pmc:PMC12079645
DO  - DOI:10.1002/alz.14307
UR  - https://pub.dzne.de/record/278782
ER  -