Home > Publications Database > The Impact of Loneliness on Late-Life Depression and Anxiety During the COVID-19 Pandemic. > print

001     278785
005     20250613100543.0
024 7 _ |a 10.1016/j.jagp.2025.01.003
|2 doi
024 7 _ |a pmid:39884877
|2 pmid
024 7 _ |a 1064-7481
|2 ISSN
024 7 _ |a 1545-7214
|2 ISSN
037 _ _ |a DZNE-2025-00621
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Müller, Julia
|b 0
245 _ _ |a The Impact of Loneliness on Late-Life Depression and Anxiety During the COVID-19 Pandemic.
260 _ _ |a [Amsterdam]
|c 2025
|b Elsevier
336 7 _ |a article
|2 DRIVER
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
|b journal
|m journal
|0 PUB:(DE-HGF)16
|s 1748938328_11720
|2 PUB:(DE-HGF)
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a Journal Article
|0 0
|2 EndNote
520 _ _ |a This study investigates the association of loneliness during the COVID-19 pandemic and the course of depressive, anxiety and sleep symptoms after psychological treatment in older adults.During the first wave of the pandemic in 2020, we assessed additional, original data of 132 participants aged ≥60 years who had completed psychological treatment for late-life depression (LLD) in the context of a multicenter, randomized controlled trial (CBT-late). We measured loneliness using the UCLA Loneliness Scale. Depression, anxiety and sleep symptoms were assessed using the Geriatric Depression Scale (GDS), Geriatric Anxiety Inventory (GAI), and Insomnia Severity Index (ISI).Participants with higher loneliness scores (n = 44) experienced a significant worsening of depressive and anxiety symptoms during the pandemic (estimated marginal mean difference (emmd) of change in GDS between post-treatment and COVID-19 visit: GDSemmd= -4.61, [95% CI: -6.97 to -2.26], GAIemmd= -2.21, [95% CI: -3.76 to -0.65]), while those with low to moderate loneliness (n = 72) maintained stable mild symptoms (GDSemmd= -1.39, [95% CI: -3.00 to 0.22], GAIemmd= -0.49, [95% CI: -1.69 to 0.72]). All patients reported increased sleep disturbances during the pandemic regardless of loneliness, while remaining in the range for sub-threshold insomnia.Our results suggest an association of significant loneliness during the COVID-19 pandemic and a clinically relevant worsening of depressive and anxiety symptoms in older adults. Loneliness assessments and interventions may be incorporated into treatments for LLD, particularly during pandemics or other crises.
536 _ _ |a 353 - Clinical and Health Care Research (POF4-353)
|0 G:(DE-HGF)POF4-353
|c POF4-353
|f POF IV
|x 0
588 _ _ |a Dataset connected to CrossRef, PubMed, , Journals: pub.dzne.de
650 _ 7 |a CBT-late
|2 Other
650 _ 7 |a COVID-19 pandemic
|2 Other
650 _ 7 |a Late-life depression
|2 Other
650 _ 7 |a loneliness
|2 Other
650 _ 7 |a older age
|2 Other
650 _ 7 |a psychological treatment
|2 Other
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Loneliness: psychology
|2 MeSH
650 _ 2 |a COVID-19: psychology
|2 MeSH
650 _ 2 |a Aged
|2 MeSH
650 _ 2 |a Male
|2 MeSH
650 _ 2 |a Female
|2 MeSH
650 _ 2 |a Anxiety: psychology
|2 MeSH
650 _ 2 |a Anxiety: therapy
|2 MeSH
650 _ 2 |a Anxiety: epidemiology
|2 MeSH
650 _ 2 |a Depression: psychology
|2 MeSH
650 _ 2 |a Depression: therapy
|2 MeSH
650 _ 2 |a Depression: epidemiology
|2 MeSH
650 _ 2 |a Middle Aged
|2 MeSH
650 _ 2 |a Aged, 80 and over
|2 MeSH
650 _ 2 |a SARS-CoV-2
|2 MeSH
650 _ 2 |a Sleep Initiation and Maintenance Disorders: psychology
|2 MeSH
700 1 _ |a Elsaesser, Moritz
|b 1
700 1 _ |a Berger, Ruben
|b 2
700 1 _ |a Müller, Wiebke
|b 3
700 1 _ |a Hellmich, Martin
|b 4
700 1 _ |a Zehender, Nadine
|b 5
700 1 _ |a Riedel-Heller, Steffi
|b 6
700 1 _ |a Bewernick, Bettina H
|b 7
700 1 _ |a Wagner, Michael
|0 P:(DE-2719)2000057
|b 8
|u dzne
700 1 _ |a Frölich, Lutz
|b 9
700 1 _ |a Peters, Oliver
|0 P:(DE-2719)2811024
|b 10
700 1 _ |a Domschke, Katharina
|b 11
700 1 _ |a Jessen, Frank
|0 P:(DE-2719)2000032
|b 12
700 1 _ |a Hautzinger, Martin
|b 13
700 1 _ |a Dafsari, Forugh S
|b 14
700 1 _ |a Schramm, Elisabeth
|b 15
773 _ _ |a 10.1016/j.jagp.2025.01.003
|g Vol. 33, no. 7, p. 717 - 729
|0 PERI:(DE-600)1474415-6
|n 7
|p 717 - 729
|t American journal of geriatric psychiatry
|v 33
|y 2025
|x 1064-7481
856 4 _ |y OpenAccess
|u https://pub.dzne.de/record/278785/files/DZNE-2025-00621.pdf
856 4 _ |y OpenAccess
|x pdfa
|u https://pub.dzne.de/record/278785/files/DZNE-2025-00621.pdf?subformat=pdfa
909 C O |o oai:pub.dzne.de:278785
|p openaire
|p open_access
|p VDB
|p driver
|p dnbdelivery
910 1 _ |a External Institute
|0 I:(DE-HGF)0
|k Extern
|b 8
|6 P:(DE-2719)2000057
910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
|0 I:(DE-588)1065079516
|k DZNE
|b 10
|6 P:(DE-2719)2811024
910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
|0 I:(DE-588)1065079516
|k DZNE
|b 12
|6 P:(DE-2719)2000032
913 1 _ |a DE-HGF
|b Gesundheit
|l Neurodegenerative Diseases
|1 G:(DE-HGF)POF4-350
|0 G:(DE-HGF)POF4-353
|3 G:(DE-HGF)POF4
|2 G:(DE-HGF)POF4-300
|4 G:(DE-HGF)POF
|v Clinical and Health Care Research
|x 0
914 1 _ |y 2025
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0200
|2 StatID
|b SCOPUS
|d 2024-12-16
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0300
|2 StatID
|b Medline
|d 2024-12-16
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0130
|2 StatID
|b Social Sciences Citation Index
|d 2024-12-16
915 _ _ |a Creative Commons Attribution CC BY 4.0
|0 LIC:(DE-HGF)CCBY4
|2 HGFVOC
915 _ _ |a JCR
|0 StatID:(DE-HGF)0100
|2 StatID
|b AM J GERIAT PSYCHIAT : 2022
|d 2024-12-16
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1180
|2 StatID
|b Current Contents - Social and Behavioral Sciences
|d 2024-12-16
915 _ _ |a WoS
|0 StatID:(DE-HGF)0113
|2 StatID
|b Science Citation Index Expanded
|d 2024-12-16
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0150
|2 StatID
|b Web of Science Core Collection
|d 2024-12-16
915 _ _ |a OpenAccess
|0 StatID:(DE-HGF)0510
|2 StatID
915 _ _ |a IF >= 5
|0 StatID:(DE-HGF)9905
|2 StatID
|b AM J GERIAT PSYCHIAT : 2022
|d 2024-12-16
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0160
|2 StatID
|b Essential Science Indicators
|d 2024-12-16
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1110
|2 StatID
|b Current Contents - Clinical Medicine
|d 2024-12-16
915 _ _ |a Nationallizenz
|0 StatID:(DE-HGF)0420
|2 StatID
|d 2024-12-16
|w ger
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0199
|2 StatID
|b Clarivate Analytics Master Journal List
|d 2024-12-16
920 1 _ |0 I:(DE-2719)5000000
|k AG Peters
|l Biomarker-Assisted Early Detection of Dementias
|x 0
920 1 _ |0 I:(DE-2719)1011102
|k AG Jessen
|l Clinical Alzheimer’s Disease Research
|x 1
980 _ _ |a journal
980 _ _ |a VDB
980 _ _ |a UNRESTRICTED
980 _ _ |a I:(DE-2719)5000000
980 _ _ |a I:(DE-2719)1011102
980 1 _ |a FullTexts

LibraryCollectionCLSMajorCLSMinorLanguageAuthor
Marc 21