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@ARTICLE{Luo:278914,
      author       = {Luo, Hao and Koponen, Marjaana and Röthlein, Christoph and
                      Becker, Cornelia and Bell, J Simon and Beyene, Kebede and
                      Chai, Yi and Chan, Amy H Y and Chui, Celine S L and
                      Haenisch, Britta and Hartikainen, Sirpa and Hsu, Amy T and
                      Ilomaki, Jenni and Kim, Ju Hwan and Knapp, Martin and
                      Kunkel, Elizabeth and Lai, Edward Chia-Cheng and Lau, Kui
                      Kai and Lau, Wallis C Y and Lee, Hyesung and Liao, Tzu-Chi
                      and Lum, Terry Y S and Man, Kenneth K C and Shin, Ju-Young
                      and Tolppanen, Anna-Maija and Wong, Gloria H Y and Wong, Ian
                      C K},
      title        = {{A} multinational cohort study of trends in survival
                      following dementia diagnosis.},
      journal      = {Communications medicine},
      volume       = {5},
      number       = {1},
      issn         = {2730-664X},
      address      = {[London]},
      publisher    = {Springer Nature},
      reportid     = {DZNE-2025-00640},
      pages        = {203},
      year         = {2025},
      abstract     = {BACKGROUND: Information on the survival of people living
                      with dementia over time and across systems can help
                      policymakers understand the real-world impact of dementia on
                      health and social care systems. This multinational cohort
                      study examines the trends in relative mortality risk
                      following a dementia diagnosis.A common protocol was applied
                      to population-based data from the UK, Germany, Finland,
                      Canada (Ontario), New Zealand, South Korea, Taiwan and Hong
                      Kong. Individuals aged 60+ with an incident dementia
                      diagnosis recorded between 2000 and 2018 were followed until
                      death or the end of the study period. Cox proportional
                      hazards regression was used to assess the association of
                      mortality in dementia patients with the year of dementia
                      diagnosis.Data from 1,272,495 individuals, with the mean age
                      at diagnosis ranging from 76.8 years (South Korea) to 82.9
                      years (Germany), show that the overall median length of
                      survival following recorded diagnosis ranges from 2.4 years
                      (New Zealand) to 7.9 years (South Korea). Hazard ratios
                      (HRs) estimated from Cox proportional hazard models decline
                      consistently over the study period in the UK, Canada, South
                      Korea, Taiwan and Hong Kong, which accounted for $84\%$ of
                      all participants. For example, the HR decreases from 0.97
                      $(95\%$ CI: 0.92-1.02) in 2001 to 0.72 (0.65-0.79) in 2016
                      in comparison to year 2000 in the UK.This study shows a
                      steady trend of decreasing risk of mortality in five out of
                      eight databases, which signals the potential positive effect
                      of dementia plans and associated policies and provides
                      reference for future policy evaluation.},
      cin          = {AG Hänisch},
      cid          = {I:(DE-2719)1013010},
      pnm          = {354 - Disease Prevention and Healthy Aging (POF4-354)},
      pid          = {G:(DE-HGF)POF4-354},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40437158},
      doi          = {10.1038/s43856-025-00923-6},
      url          = {https://pub.dzne.de/record/278914},
}