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@INBOOK{Berron:278928,
      author       = {Berron, David},
      title        = {{A}dvances in cognitive testing},
      publisher    = {Elsevier},
      reportid     = {DZNE-2025-00654},
      pages        = {161 - 184},
      year         = {2025},
      comment      = {Early Detection in Alzheimer' s Disease / Berron, David ; :
                      Elsevier, 2025, ; ISBN: 9780128222409 ;
                      doi:10.1016/B978-0-12-822240-9.00009-0},
      booktitle     = {Early Detection in Alzheimer' s
                       Disease / Berron, David ; : Elsevier,
                       2025, ; ISBN: 9780128222409 ;
                       doi:10.1016/B978-0-12-822240-9.00009-0},
      abstract     = {Recent developments in Alzheimer's disease biomarkers have
                      significantly improved the early detection of Alzheimer's
                      disease pathology (Hansson et al., 2023; Ossenkoppele and
                      Hansson, 2021; Zetterberg and Blennow, 2021) [1-3]. However,
                      while biomarkers for Alzheimer's disease can indicate the
                      underlying brain pathology and have some predictive value
                      for future cognitive decline, they do not provide
                      information about cognitive Alzheimer's disease phenotypes,
                      particularly in early disease stages (Dubois et al., 2021)
                      [4], nor do they represent optimal measures of disease
                      progression. Thus, it is of critical importance to identify,
                      characterize, and monitor cognitive impairment in
                      Alzheimer's disease using cognitive assessments. While
                      capturing subtle cognitive changes and impairment in early
                      disease stages still remains challenging (Weintraub et al.,
                      2018) [5], several new approaches have recently been
                      utilized to improve the early detection of subtle cognitive
                      impairment and decline. In this chapter, I will first
                      provide an overview of novel cognitive test paradigms that
                      are tailored toward cognitive functions of which the
                      functional anatomy overlaps with spatial patterns of
                      accumulation of Alzheimer's disease pathology; these
                      paradigms aim to capture signs of early impairment with
                      greater sensitivity than previous measures. I will then
                      illustrate new approaches to cognitive testing that build on
                      recent technological developments (Koo and Vizer, 2019;
                      Kourtis et al., 2019) [6,7] and aim to assess cognitive
                      performance even outside clinical settings.},
      cin          = {AG Berron},
      cid          = {I:(DE-2719)5000070},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)7},
      doi          = {10.1016/B978-0-12-822240-9.00009-0},
      url          = {https://pub.dzne.de/record/278928},
}