guest ::
| Home > Publications Database > A public benchmark for human performance in the detection of focal cortical dysplasia. > print |
| Home > Publications Database > A public benchmark for human performance in the detection of focal cortical dysplasia. > print |
| 001 | 279188 | ||
| 005 | 20250713001426.0 | ||
| 024 | 7 | _ | |a 10.1002/epi4.70028 |2 doi |
| 024 | 7 | _ | |a pmid:40167314 |2 pmid |
| 024 | 7 | _ | |a altmetric:176012064 |2 altmetric |
| 037 | _ | _ | |a DZNE-2025-00716 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Walger, Lennart |0 0000-0002-3300-6877 |b 0 |
| 245 | _ | _ | |a A public benchmark for human performance in the detection of focal cortical dysplasia. |
| 260 | _ | _ | |a Hoboken, NJ |c 2025 |b Wiley |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1751973496_30314 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a This study aims to report human performance in the detection of Focal Cortical Dysplasias (FCDs) using an openly available dataset. Additionally, it defines a subset of this data as a 'difficult' test set to establish a public baseline benchmark against which new methods for automated FCD detection can be evaluated.The performance of 28 human readers with varying levels of expertise in detecting FCDs was originally analyzed using 146 subjects (not all of which are openly available), we analyzed the openly available subset of 85 cases. Performance was measured based on the overlap between predicted regions of interest (ROIs) and ground-truth lesion masks, using the Dice-Soerensen coefficient (DSC). The benchmark test set was chosen to consist of 15 subjects most predictive for human performance and 13 subjects identified by at most 3 of the 28 readers.Expert readers achieved an average detection rate of 68%, compared to 45% for non-experts and 27% for laypersons. Neuroradiologists detected the highest percentage of lesions (64%), while psychiatrists detected the least (34%). Neurosurgeons had the highest ROI sensitivity (0.70), and psychiatrists had the highest ROI precision (0.78). The benchmark test set revealed an expert detection rate of 49%.Reporting human performance in FCD detection provides a critical baseline for assessing the effectiveness of automated detection methods in a clinically relevant context. The defined benchmark test set serves as a useful indicator for evaluating advancements in computer-aided FCD detection approaches.Focal cortical dysplasias (FCDs) are malformations of cortical development and one of the most common causes of drug-resistant focal epilepsy. Once found, FCDs can be neurosurgically resected, which leads to seizure freedom in many cases. However, FCDs are difficult to detect in the visual assessment of magnetic resonance imaging. A myriad of algorithms for automated FCD detection have been developed, but their true clinical value remains unclear since there is no benchmark dataset for evaluation and comparison to human performance. Here, we use human FCD detection performance to define a benchmark dataset with which new methods for automated detection can be evaluated. |
| 536 | _ | _ | |a 354 - Disease Prevention and Healthy Aging (POF4-354) |0 G:(DE-HGF)POF4-354 |c POF4-354 |f POF IV |x 0 |
| 536 | _ | _ | |a 353 - Clinical and Health Care Research (POF4-353) |0 G:(DE-HGF)POF4-353 |c POF4-353 |f POF IV |x 1 |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, , Journals: pub.dzne.de |
| 650 | _ | 7 | |a artificial intelligence |2 Other |
| 650 | _ | 7 | |a computer‐aided detection |2 Other |
| 650 | _ | 7 | |a human performance |2 Other |
| 650 | _ | 7 | |a reader study |2 Other |
| 650 | _ | 2 | |a Humans |2 MeSH |
| 650 | _ | 2 | |a Benchmarking |2 MeSH |
| 650 | _ | 2 | |a Malformations of Cortical Development: diagnostic imaging |2 MeSH |
| 650 | _ | 2 | |a Malformations of Cortical Development: diagnosis |2 MeSH |
| 650 | _ | 2 | |a Magnetic Resonance Imaging |2 MeSH |
| 650 | _ | 2 | |a Female |2 MeSH |
| 650 | _ | 2 | |a Male |2 MeSH |
| 650 | _ | 2 | |a Adult |2 MeSH |
| 650 | _ | 2 | |a Focal Cortical Dysplasia |2 MeSH |
| 700 | 1 | _ | |a Schmitz, Matthias H |0 P:(DE-HGF)0 |b 1 |
| 700 | 1 | _ | |a Bauer, Tobias |0 P:(DE-2719)9002598 |b 2 |
| 700 | 1 | _ | |a Kügler, David |0 P:(DE-2719)2814290 |b 3 |u dzne |
| 700 | 1 | _ | |a Schuch, Fabiane |b 4 |
| 700 | 1 | _ | |a Arendt, Christophe |b 5 |
| 700 | 1 | _ | |a Baumgartner, Tobias |0 0000-0001-5935-9841 |b 6 |
| 700 | 1 | _ | |a Birkenheier, Johannes |b 7 |
| 700 | 1 | _ | |a Borger, Valeri |0 0000-0002-5905-4121 |b 8 |
| 700 | 1 | _ | |a Endler, Christoph |b 9 |
| 700 | 1 | _ | |a Grau, Franziska |b 10 |
| 700 | 1 | _ | |a Immanuel, Christian |b 11 |
| 700 | 1 | _ | |a Kölle, Markus |b 12 |
| 700 | 1 | _ | |a Kupczyk, Patrick |b 13 |
| 700 | 1 | _ | |a Lakghomi, Asadeh |b 14 |
| 700 | 1 | _ | |a Mackert, Sarah |b 15 |
| 700 | 1 | _ | |a Neuhaus, Elisabeth |b 16 |
| 700 | 1 | _ | |a Nordsiek, Julia |b 17 |
| 700 | 1 | _ | |a Odenthal, Anna-Maria |b 18 |
| 700 | 1 | _ | |a Dague, Karmele Olaciregui |b 19 |
| 700 | 1 | _ | |a Ostermann, Laura |b 20 |
| 700 | 1 | _ | |a Pukropski, Jan |0 0000-0002-8280-6475 |b 21 |
| 700 | 1 | _ | |a Racz, Attila |b 22 |
| 700 | 1 | _ | |a von der Ropp, Klaus |b 23 |
| 700 | 1 | _ | |a Schmeel, Frederic Carsten |b 24 |
| 700 | 1 | _ | |a Schrader, Felix |b 25 |
| 700 | 1 | _ | |a Sitter, Aileen |b 26 |
| 700 | 1 | _ | |a Unruh-Pinheiro, Alexander |b 27 |
| 700 | 1 | _ | |a Voigt, Marilia |b 28 |
| 700 | 1 | _ | |a Vychopen, Martin |b 29 |
| 700 | 1 | _ | |a von Wedel, Philip |b 30 |
| 700 | 1 | _ | |a von Wrede, Randi |0 0000-0002-9430-5037 |b 31 |
| 700 | 1 | _ | |a Attenberger, Ulrike |b 32 |
| 700 | 1 | _ | |a Vatter, Hartmut |b 33 |
| 700 | 1 | _ | |a Philipsen, Alexandra |b 34 |
| 700 | 1 | _ | |a Becker, Albert |b 35 |
| 700 | 1 | _ | |a Reuter, Martin |0 P:(DE-2719)2812134 |b 36 |u dzne |
| 700 | 1 | _ | |a Hattingen, Elke |b 37 |
| 700 | 1 | _ | |a Radbruch, Alexander |0 P:(DE-2719)9001861 |b 38 |u dzne |
| 700 | 1 | _ | |a Surges, Rainer |0 0000-0002-3177-8582 |b 39 |
| 700 | 1 | _ | |a Rüber, Theodor |0 0000-0002-6180-7671 |b 40 |e Last author |
| 773 | _ | _ | |a 10.1002/epi4.70028 |g Vol. 10, no. 3, p. 778 - 786 |0 PERI:(DE-600)2863427-5 |n 3 |p 778 - 786 |t Epilepsia open |v 10 |y 2025 |x 2470-9239 |
| 856 | 4 | _ | |y OpenAccess |u https://pub.dzne.de/record/279188/files/DZNE-2025-00716.pdf |
| 856 | 4 | _ | |y OpenAccess |x pdfa |u https://pub.dzne.de/record/279188/files/DZNE-2025-00716.pdf?subformat=pdfa |
| 909 | C | O | |o oai:pub.dzne.de:279188 |p openaire |p open_access |p VDB |p driver |p dnbdelivery |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 2 |6 P:(DE-2719)9002598 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 3 |6 P:(DE-2719)2814290 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 36 |6 P:(DE-2719)2812134 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 38 |6 P:(DE-2719)9001861 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 40 |6 0000-0002-6180-7671 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Neurodegenerative Diseases |1 G:(DE-HGF)POF4-350 |0 G:(DE-HGF)POF4-354 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-300 |4 G:(DE-HGF)POF |v Disease Prevention and Healthy Aging |x 0 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Neurodegenerative Diseases |1 G:(DE-HGF)POF4-350 |0 G:(DE-HGF)POF4-353 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-300 |4 G:(DE-HGF)POF |v Clinical and Health Care Research |x 1 |
| 914 | 1 | _ | |y 2025 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |d 2024-12-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0160 |2 StatID |b Essential Science Indicators |d 2024-12-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1030 |2 StatID |b Current Contents - Life Sciences |d 2024-12-05 |
| 915 | _ | _ | |a Creative Commons Attribution CC BY 4.0 |0 LIC:(DE-HGF)CCBY4 |2 HGFVOC |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |b EPILEPSIA OPEN : 2022 |d 2024-12-05 |
| 915 | _ | _ | |a DEAL Wiley |0 StatID:(DE-HGF)3001 |2 StatID |d 2024-12-05 |w ger |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0500 |2 StatID |b DOAJ |d 2024-08-08T17:09:27Z |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0501 |2 StatID |b DOAJ Seal |d 2024-08-08T17:09:27Z |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0113 |2 StatID |b Science Citation Index Expanded |d 2024-12-05 |
| 915 | _ | _ | |a Fees |0 StatID:(DE-HGF)0700 |2 StatID |d 2024-12-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |d 2024-12-05 |
| 915 | _ | _ | |a IF < 5 |0 StatID:(DE-HGF)9900 |2 StatID |d 2024-12-05 |
| 915 | _ | _ | |a OpenAccess |0 StatID:(DE-HGF)0510 |2 StatID |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b DOAJ : Anonymous peer review |d 2024-08-08T17:09:27Z |
| 915 | _ | _ | |a Article Processing Charges |0 StatID:(DE-HGF)0561 |2 StatID |d 2024-12-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2024-12-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1110 |2 StatID |b Current Contents - Clinical Medicine |d 2024-12-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Clarivate Analytics Master Journal List |d 2024-12-05 |
| 920 | 1 | _ | |0 I:(DE-2719)1040310 |k AG Reuter |l Artificial Intelligence in Medicine |x 0 |
| 920 | 1 | _ | |0 I:(DE-2719)1013026 |k AG Stöcker |l MR Physics |x 1 |
| 920 | 1 | _ | |0 I:(DE-2719)5000075 |k AG Radbruch |l Clinical Neuroimaging |x 2 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a UNRESTRICTED |
| 980 | _ | _ | |a I:(DE-2719)1040310 |
| 980 | _ | _ | |a I:(DE-2719)1013026 |
| 980 | _ | _ | |a I:(DE-2719)5000075 |
| 980 | 1 | _ | |a FullTexts |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|