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000279378 1001_ $$00009-0009-4542-3000$$aPorsche, Sonja$$b0
000279378 245__ $$aA Short Cognitive and Neuropsychiatric Assessment Scale for Progressive Supranuclear Palsy.
000279378 260__ $$aNew York, NY$$bWiley$$c2025
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000279378 520__ $$aPatients with Progressive Supranuclear Palsy (PSP) suffer from several neuropsychological impairments. These mainly affect the frontal lobe and subcortical brain structures. However, a scale for the assessment of cognitive and neuropsychiatric disability in PSP is still missing.To create and validate a new scale for cognitive and neuropsychiatric impairment in PSP.The Short Cognitive and Neuropsychiatric (ShoCo) scale was developed containing five items (bradyphrenia, apathy, aphasia, dysexecution and disinhibition). Each item can be categorized into 0 = no deficit, 1 = mild deficit, 2 = moderate deficit and 3 = severe deficit. The total score includes 15 points, 0 meaning no deficit and 15 severe deficits. Cross-sectional and longitudinal data from 201 baseline and 71 follow up patients were analyzed.Baseline ShoCo scale results were 5.9 ± 2.9. No significant differences between patients with Richardson syndrome (PSP-RS) and variants (vPSP) could be detected in the PSP-ShoCo scale scores (PSP-RS 6.1 ± 3.0, n = 160, vPSP 5.1 ± 2.6, n = 41, P = 0.057). The scale showed good correlation with established scores (eg, Montreal cognitive assessment r = -0.535, P = 0.001). The ShoCo scale showed significant annualized change within the PSP-RS patients (baseline 6.2 ± 2.9, follow up 6.9 ± 3.1, annualized diff. 1.0 ± 3.1, n = 57, P = 0.022).The ShoCo scale seems a promising and valid tool to measure specific neuropsychological disabilities of PSP patients in clinical routine and research.
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000279378 650_7 $$2Other$$a4‐repeat tauopathies
000279378 650_7 $$2Other$$aProgressive Supranuclear Palsy
000279378 650_7 $$2Other$$acognition
000279378 650_7 $$2Other$$adepression
000279378 650_7 $$2Other$$aquality of life
000279378 650_2 $$2MeSH$$aHumans
000279378 650_2 $$2MeSH$$aSupranuclear Palsy, Progressive: complications
000279378 650_2 $$2MeSH$$aSupranuclear Palsy, Progressive: diagnosis
000279378 650_2 $$2MeSH$$aSupranuclear Palsy, Progressive: psychology
000279378 650_2 $$2MeSH$$aMale
000279378 650_2 $$2MeSH$$aFemale
000279378 650_2 $$2MeSH$$aAged
000279378 650_2 $$2MeSH$$aNeuropsychological Tests
000279378 650_2 $$2MeSH$$aCross-Sectional Studies
000279378 650_2 $$2MeSH$$aMiddle Aged
000279378 650_2 $$2MeSH$$aAged, 80 and over
000279378 650_2 $$2MeSH$$aLongitudinal Studies
000279378 650_2 $$2MeSH$$aSeverity of Illness Index
000279378 7001_ $$00000-0002-3054-9905$$aKlietz, Martin$$b1
000279378 7001_ $$00000-0003-0638-8571$$aGreten, Stephan$$b2
000279378 7001_ $$0P:(DE-2719)9000949$$aPiot, Ines$$b3
000279378 7001_ $$0P:(DE-2719)9003066$$aJensen, Ida$$b4
000279378 7001_ $$aWegner, Florian$$b5
000279378 7001_ $$aYe, Lan$$b6
000279378 7001_ $$aKrey, Lea$$b7
000279378 7001_ $$0P:(DE-2719)2813308$$aHöllerhage, Matthias$$b8
000279378 7001_ $$00000-0001-7680-2147$$aPötter-Nerger, Monika$$b9
000279378 7001_ $$aZeitzschel, Molly$$b10
000279378 7001_ $$aHagena, Keno$$b11
000279378 7001_ $$0P:(DE-2719)9001967$$aKassubek, Jan$$b12
000279378 7001_ $$aSüß, Patrick$$b13
000279378 7001_ $$aWinkler, Jürgen$$b14
000279378 7001_ $$aBerg, Daniela$$b15
000279378 7001_ $$aPaschen, Steffen$$b16
000279378 7001_ $$00000-0001-6621-144X$$aTönges, Lars$$b17
000279378 7001_ $$aGruber, Doreen$$b18
000279378 7001_ $$00000-0003-2874-9817$$aGandor, Florin$$b19
000279378 7001_ $$00000-0002-8574-3297$$aJost, Wolfgang H$$b20
000279378 7001_ $$0P:(DE-2719)2811089$$aKühn, Andrea A$$b21$$udzne
000279378 7001_ $$aClaus, Inga$$b22
000279378 7001_ $$aWarnecke, Tobias$$b23
000279378 7001_ $$aPedrosa, David J$$b24
000279378 7001_ $$aEggers, Carsten$$b25
000279378 7001_ $$aTrenkwalder, Claudia$$b26
000279378 7001_ $$aClassen, Joseph$$b27
000279378 7001_ $$aSchwarz, Johannes$$b28
000279378 7001_ $$aSchnitzler, Alfons$$b29
000279378 7001_ $$00000-0001-9063-0556$$aKrause, Patricia$$b30
000279378 7001_ $$0P:(DE-2719)2812035$$aSchneider, Anja$$b31
000279378 7001_ $$0P:(DE-2719)2812107$$aBrandt, Moritz$$b32$$udzne
000279378 7001_ $$0P:(DE-2719)2814178$$aFalkenburger, Björn$$b33$$udzne
000279378 7001_ $$0P:(DE-2719)2000058$$aZerr, Inga$$b34$$udzne
000279378 7001_ $$0P:(DE-2719)2811350$$aBähr, Mathias$$b35$$udzne
000279378 7001_ $$0P:(DE-2719)9000882$$aWeidinger, Endy$$b36$$udzne
000279378 7001_ $$0P:(DE-2719)2811659$$aLevin, Johannes$$b37$$udzne
000279378 7001_ $$0P:(DE-2719)9001160$$aKatzdobler, Sabrina$$b38
000279378 7001_ $$0P:(DE-2719)2000005$$aDüzel, Emrah$$b39$$udzne
000279378 7001_ $$0P:(DE-2719)2811614$$aGlanz, Wenzel$$b40$$udzne
000279378 7001_ $$0P:(DE-2719)2000026$$aTeipel, Stefan$$b41$$udzne
000279378 7001_ $$0P:(DE-2719)2810394$$aKilimann, Ingo$$b42$$udzne
000279378 7001_ $$0P:(DE-2719)2380559$$aPrudlo, Johannes$$b43$$udzne
000279378 7001_ $$0P:(DE-2719)2320009$$aGasser, Thomas$$b44$$udzne
000279378 7001_ $$0P:(DE-2719)2811916$$aBrockmann, Kathrin$$b45
000279378 7001_ $$0P:(DE-2719)2811324$$aSpottke, Annika$$b46$$udzne
000279378 7001_ $$0P:(DE-2719)9002699$$aEsser, Anna$$b47$$udzne
000279378 7001_ $$0P:(DE-2719)2810273$$aPetzold, Gabor C$$b48$$udzne
000279378 7001_ $$0P:(DE-2719)2811600$$aRespondek, Gesine$$b49
000279378 7001_ $$0P:(DE-2719)2811373$$aHöglinger, Günter U$$b50$$udzne
000279378 773__ $$0PERI:(DE-600)2772809-2$$a10.1002/mdc3.14348$$gVol. 12, no. 6, p. 764 - 774$$n6$$p764 - 774$$tMovement disorders clinical practice$$v12$$x2330-1619$$y2025
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