000279473 001__ 279473
000279473 005__ 20250710100950.0
000279473 0247_ $$2doi$$a10.5061/DRYAD.XGXD254RB
000279473 0247_ $$2doi$$a10.5061/dryad.xgxd254rb
000279473 037__ $$aDZNE-2025-00800
000279473 041__ $$aEnglish
000279473 1001_ $$0P:(DE-2719)2000011$$aKempermann, Gerd$$b0
000279473 245__ $$aDataset: Individual choices shape divergent brains and behaviors
000279473 260__ $$bDryad$$c2025
000279473 3367_ $$2BibTeX$$aMISC
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000279473 520__ $$aIndividual choices shape life course trajectories of brain structure and function beyond genes and environment. We hypothesized that individual task engagement in response to a learning program results in individualized learning biographies and connectomics. Genetically identical female mice living in one large shared enclosure freely engaged in self-paced, automatically administered and monitored learning tasks. We discovered growing and increasingly stable inter-individual differences in learning trajectories. Adult hippocampal neurogenesis and connectivity as assessed by a high-density multi-electrode array positively correlated with the variation in exploration and learning efficiency. During some tasks, divergence transiently collapsed, highlighting the sustained significance of context for individualization. Thus, equal environments and equal genes do not result in equal learning biographies because life confronts individuals with choices that lead to divergent paths.
000279473 536__ $$0G:(DE-HGF)POF4-351$$a351 - Brain Function (POF4-351)$$cPOF4-351$$fPOF IV$$x0
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000279473 588__ $$aDataset connected to DataCite
000279473 650_7 $$2Other$$aIndividuality
000279473 650_7 $$2Other$$aBehavior
000279473 650_7 $$2Other$$aLearning
000279473 650_7 $$2Other$$amouse
000279473 650_7 $$2Other$$atracking
000279473 650_7 $$2Other$$aIntellicage
000279473 650_7 $$2Other$$aFOS: Biological sciences
000279473 7001_ $$0P:(DE-2719)9001855$$aBarde, Warsha$$b1$$udzne
000279473 7001_ $$0P:(DE-HGF)0$$aRenner, Jonas$$b2
000279473 7001_ $$0P:(DE-2719)9001361$$aEmery, Brett$$b3$$udzne
000279473 7001_ $$0P:(DE-HGF)0$$aKhanzada, Shakrukh$$b4
000279473 7001_ $$0P:(DE-2719)2814182$$aHu, Xin$$b5$$udzne
000279473 7001_ $$0P:(DE-2719)2810535$$aGarthe, Alexander$$b6$$udzne
000279473 7001_ $$0P:(DE-2719)2810792$$aRünker, Annette$$b7$$udzne
000279473 7001_ $$0P:(DE-2719)2812628$$aAmin, Hayder$$b8$$udzne
000279473 773__ $$a10.5061/dryad.xgxd254rb
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000279473 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2000011$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b0$$kDZNE
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000279473 9131_ $$0G:(DE-HGF)POF4-351$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vBrain Function$$x0
000279473 9131_ $$0G:(DE-HGF)POF4-352$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vDisease Mechanisms$$x1
000279473 9141_ $$y2025
000279473 9201_ $$0I:(DE-2719)1710010$$kAG Amin$$lBiohybrid Neuroelectronics (BIONICS)$$x0
000279473 9201_ $$0I:(DE-2719)1710001$$kAG Kempermann$$lAdult Neurogenesis$$x1
000279473 9201_ $$0I:(DE-2719)1740001$$kAG Garthe$$lNeurobiology of Behaviour$$x2
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