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@MISC{Kempermann:279473,
      author       = {Kempermann, Gerd and Barde, Warsha and Renner, Jonas and
                      Emery, Brett and Khanzada, Shakrukh and Hu, Xin and Garthe,
                      Alexander and Rünker, Annette and Amin, Hayder},
      title        = {{D}ataset: {I}ndividual choices shape divergent brains and
                      behaviors},
      publisher    = {Dryad},
      reportid     = {DZNE-2025-00800},
      year         = {2025},
      abstract     = {Individual choices shape life course trajectories of brain
                      structure and function beyond genes and environment. We
                      hypothesized that individual task engagement in response to
                      a learning program results in individualized learning
                      biographies and connectomics. Genetically identical female
                      mice living in one large shared enclosure freely engaged in
                      self-paced, automatically administered and monitored
                      learning tasks. We discovered growing and increasingly
                      stable inter-individual differences in learning
                      trajectories. Adult hippocampal neurogenesis and
                      connectivity as assessed by a high-density multi-electrode
                      array positively correlated with the variation in
                      exploration and learning efficiency. During some tasks,
                      divergence transiently collapsed, highlighting the sustained
                      significance of context for individualization. Thus, equal
                      environments and equal genes do not result in equal learning
                      biographies because life confronts individuals with choices
                      that lead to divergent paths.},
      keywords     = {Individuality (Other) / Behavior (Other) / Learning (Other)
                      / mouse (Other) / tracking (Other) / Intellicage (Other) /
                      FOS: Biological sciences (Other)},
      cin          = {AG Amin / AG Kempermann / AG Garthe},
      cid          = {I:(DE-2719)1710010 / I:(DE-2719)1710001 /
                      I:(DE-2719)1740001},
      pnm          = {351 - Brain Function (POF4-351) / 352 - Disease Mechanisms
                      (POF4-352)},
      pid          = {G:(DE-HGF)POF4-351 / G:(DE-HGF)POF4-352},
      typ          = {PUB:(DE-HGF)32},
      doi          = {10.5061/dryad.xgxd254rb},
      url          = {https://pub.dzne.de/record/279473},
}