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@ARTICLE{Labott:279887,
      author       = {Labott, Berit K and Herold, Fabian and Langhans, Corinna
                      and Halfpaap, Nicole and Grässler, Bernhard and Hökelmann,
                      Anita and Müller, Notger G and Hamacher, Daniel},
      title        = {{M}inimum toe clearance variability in older adults with
                      mild cognitive impairment: {D}ifferences to healthy controls
                      and effects of a dance intervention.},
      journal      = {Gait $\&$ posture},
      volume       = {121},
      issn         = {0966-6362},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {DZNE-2025-00854},
      pages        = {101 - 107},
      year         = {2025},
      abstract     = {Falls in older adults with mild cognitive impairment (MCI)
                      are a major health issue. For healthy individuals, higher
                      variability in minimum toe clearance (MTC) during gait is
                      associated with the risk of tripping-related falls and dance
                      intervention reduces MTC variability. Such empirical
                      evidence is lacking for individuals with MCI.We aimed to
                      assess differences in MTC variability between healthy older
                      adults and older adults with MCI. Furthermore, we analysed
                      the effects of a six-month dance intervention on MTC
                      variability in older adults with MCI.We recruited
                      community-dwelling cognitively healthy control participants
                      (n = 34) and participants with MCI (n = 55). All
                      participants underwent gait assessment using inertial
                      sensors. In a cohort study, MTC variability of healthy vs.
                      MCI participants was compared using Welch's t-test. There
                      were no significant differences in the participant's
                      characteristics except for cognitive performance. In a
                      randomised controlled trial, participants with MCI were
                      randomly allocated to either an intervention (IG, n = 27) or
                      a passive control group (CG, n = 28). IG was required to
                      attend a twice-weekly 90-minute dance program for six
                      months. After six months, the gait assessment was repeated
                      in both groups of MCI participants, and the effect of the
                      dance intervention on MTC variability was assessed using
                      2-level random intercept models. Additionally, the mean MTC
                      was analysed in a secondary analysis.Adults with MCI
                      exhibited a significantly higher MTC variability compared to
                      healthy adults (p = .016, d = 0.53), but no difference was
                      found in the mean MTC (p = .980, d < 0.01). The dance
                      intervention did not improve either MTC variability (p =
                      .182) or mean MTC (p = .742).The higher MTC variability in
                      older adults with MCI compared to healthy controls may
                      contribute to their higher fall risk. Future studies should
                      investigate the effects of an individually tailored dance
                      intervention, and other intervention approaches on MTC
                      variability and fall risk.},
      keywords     = {Humans / Cognitive Dysfunction: physiopathology / Cognitive
                      Dysfunction: rehabilitation / Aged / Male / Female / Dance
                      Therapy: methods / Toes: physiopathology / Toes: physiology
                      / Gait: physiology / Accidental Falls: prevention $\&$
                      control / Case-Control Studies / Aged, 80 and over /
                      Dancing: physiology / Postural Balance: physiology /
                      Geriatrics (Other) / Inertial sensor (Other) / Locomotion
                      (Other) / Minimum foot clearance (Other) / Minor
                      neurocognitive disorder (Other) / Primary prevention
                      (Other)},
      cin          = {AG Müller},
      ddc          = {796},
      cid          = {I:(DE-2719)1310003},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40339306},
      doi          = {10.1016/j.gaitpost.2025.04.033},
      url          = {https://pub.dzne.de/record/279887},
}