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000280057 1001_ $$00000-0002-3957-9553$$aSpijker, Jeroen J A$$b0
000280057 245__ $$aEducational inequalities in dementia-related mortality using a multiple cause of death approach and their contribution to life expectancy differences in Spain.
000280057 260__ $$a[London]$$bSpringer Nature$$c2025
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000280057 520__ $$aWe examine dementia-related mortality in Spain from 2016 to 2021, focusing on its comorbidities and educational inequalities in life expectancy at age 60. Using a multiple cause of death (MCOD) approach, we assess how dementia-related mortality varies by education level and how these differences contribute to disparities in longevity. We used mortality data from the Spanish National Statistics Institute (INE) by level of education from 2016 to 2021 to analyse mortality from dementia-related diseases (ICD-10 codes: F01-F03, G30-G31) both as underlying cause of death (UCOD) and as MCOD (irrespective of their position within the death certificate). We estimated age-standardized mortality rates and used life tables and demographic decomposition techniques to assess the impact of dementia-related diseases on educational differences in life expectancy at age 60. Results showed that in 2016-21 MCOD dementia-related deaths accounted for 17% of all deaths occurring after the age of 60 (men: 11%; women 21%). The higher MCOD dementia-related mortality experienced by the lower educated group contributed 0.13 years (8.4%) to the total life expectancy gap at age 60 between the low and high education groups for men, and 0.26 years (22.7%) for women. Educational gradients in dementia-related mortality in Spain highlight the importance of disentangling risk factors from a socioeconomic perspective. Moreover, the MCOD approach provides a more realistic estimate of the impact of dementia-related diseases on life expectancy, bringing insights into the burden of ageing-related diseases.
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000280057 650_7 $$2Other$$aDecomposition
000280057 650_7 $$2Other$$aDementia
000280057 650_7 $$2Other$$aEducation
000280057 650_7 $$2Other$$aInequalities
000280057 650_7 $$2Other$$aMultiple causes of death
000280057 650_2 $$2MeSH$$aHumans
000280057 650_2 $$2MeSH$$aDementia: mortality
000280057 650_2 $$2MeSH$$aSpain: epidemiology
000280057 650_2 $$2MeSH$$aLife Expectancy
000280057 650_2 $$2MeSH$$aFemale
000280057 650_2 $$2MeSH$$aMale
000280057 650_2 $$2MeSH$$aAged
000280057 650_2 $$2MeSH$$aEducational Status
000280057 650_2 $$2MeSH$$aMiddle Aged
000280057 650_2 $$2MeSH$$aCause of Death
000280057 650_2 $$2MeSH$$aAged, 80 and over
000280057 650_2 $$2MeSH$$aSocioeconomic Factors
000280057 7001_ $$00000-0002-6215-3251$$aCalazans, Júlia Almeida$$b1
000280057 7001_ $$00000-0002-8052-6736$$aTrias-Llimós, Sergi$$b2
000280057 7001_ $$00000-0002-7072-8465$$aRenteria, Elisenda$$b3
000280057 7001_ $$0P:(DE-2719)2811246$$aDoblhammer, Gabriele$$b4$$eLast author
000280057 773__ $$0PERI:(DE-600)2615211-3$$a10.1038/s41598-025-10079-x$$gVol. 15, no. 1, p. 26838$$n1$$p26838$$tScientific reports$$v15$$x2045-2322$$y2025
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