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001     280057
005     20250824001737.0
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037 _ _ |a DZNE-2025-00894
041 _ _ |a English
082 _ _ |a 600
100 1 _ |a Spijker, Jeroen J A
|0 0000-0002-3957-9553
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245 _ _ |a Educational inequalities in dementia-related mortality using a multiple cause of death approach and their contribution to life expectancy differences in Spain.
260 _ _ |a [London]
|c 2025
|b Springer Nature
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520 _ _ |a We examine dementia-related mortality in Spain from 2016 to 2021, focusing on its comorbidities and educational inequalities in life expectancy at age 60. Using a multiple cause of death (MCOD) approach, we assess how dementia-related mortality varies by education level and how these differences contribute to disparities in longevity. We used mortality data from the Spanish National Statistics Institute (INE) by level of education from 2016 to 2021 to analyse mortality from dementia-related diseases (ICD-10 codes: F01-F03, G30-G31) both as underlying cause of death (UCOD) and as MCOD (irrespective of their position within the death certificate). We estimated age-standardized mortality rates and used life tables and demographic decomposition techniques to assess the impact of dementia-related diseases on educational differences in life expectancy at age 60. Results showed that in 2016-21 MCOD dementia-related deaths accounted for 17% of all deaths occurring after the age of 60 (men: 11%; women 21%). The higher MCOD dementia-related mortality experienced by the lower educated group contributed 0.13 years (8.4%) to the total life expectancy gap at age 60 between the low and high education groups for men, and 0.26 years (22.7%) for women. Educational gradients in dementia-related mortality in Spain highlight the importance of disentangling risk factors from a socioeconomic perspective. Moreover, the MCOD approach provides a more realistic estimate of the impact of dementia-related diseases on life expectancy, bringing insights into the burden of ageing-related diseases.
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650 _ 7 |a Decomposition
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650 _ 7 |a Dementia
|2 Other
650 _ 7 |a Education
|2 Other
650 _ 7 |a Inequalities
|2 Other
650 _ 7 |a Multiple causes of death
|2 Other
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Dementia: mortality
|2 MeSH
650 _ 2 |a Spain: epidemiology
|2 MeSH
650 _ 2 |a Life Expectancy
|2 MeSH
650 _ 2 |a Female
|2 MeSH
650 _ 2 |a Male
|2 MeSH
650 _ 2 |a Aged
|2 MeSH
650 _ 2 |a Educational Status
|2 MeSH
650 _ 2 |a Middle Aged
|2 MeSH
650 _ 2 |a Cause of Death
|2 MeSH
650 _ 2 |a Aged, 80 and over
|2 MeSH
650 _ 2 |a Socioeconomic Factors
|2 MeSH
700 1 _ |a Calazans, Júlia Almeida
|0 0000-0002-6215-3251
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700 1 _ |a Trias-Llimós, Sergi
|0 0000-0002-8052-6736
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700 1 _ |a Renteria, Elisenda
|0 0000-0002-7072-8465
|b 3
700 1 _ |a Doblhammer, Gabriele
|0 P:(DE-2719)2811246
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|e Last author
773 _ _ |a 10.1038/s41598-025-10079-x
|g Vol. 15, no. 1, p. 26838
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910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
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