TY  - JOUR
AU  - Mietzner, Grazia
AU  - Lümkemann, Lilli
AU  - Schreiber, Frank
AU  - Brüggemann, Jascha
AU  - Benramadan, Abrar
AU  - Al-Dubai, Marwa
AU  - Sciarra, Alessandro
AU  - Knoll, Christoph
AU  - Kuehn, Esther
AU  - Speck, Oliver
AU  - Schreiber, Stefanie
AU  - Mattern, Hendrik
TI  - Assessing Arterial Patterns in the Motor Cortex With 7 Tesla Magnetic Resonance Imaging and Vessel Distance Mapping.
JO  - Human brain mapping
VL  - 46
IS  - 11
SN  - 1065-9471
CY  - New York, NY
PB  - Wiley-Liss
M1  - DZNE-2025-00905
SP  - e70311
PY  - 2025
AB  - Leveraging high-resolution 7 T magnetic resonance imaging (MRI) and vessel distance mapping (VDM), the arterial supply patterns and dominances of the motor cortex, which could previously only be studied postmortem, were assessed in vivo and fully noninvasively. Beyond vessel patterns and dominances, the potential relation between the vascularization and the motor cortex thickness was studied. Twenty-one healthy participants underwent 7 T MRI scans to map arterial supply and motor cortex at 0.45 mm isotropic resolution. The motor cortex vasculature was segmented manually with vessel-specific labels. VDM was utilized to estimate the vessel-specific supply regions and, subsequently, assess vessel patterns and dominances. Statistical tests were applied to test if the vasculature impacts mean motor cortical thickness estimates. Vessel patterns, that is the presence of supplying vessels, were classified as three-, four-, and five-vessel patterns with a prevalence of 26.3
KW  - Humans
KW  - Motor Cortex: blood supply
KW  - Motor Cortex: diagnostic imaging
KW  - Motor Cortex: anatomy & histology
KW  - Male
KW  - Magnetic Resonance Imaging: methods
KW  - Female
KW  - Adult
KW  - Young Adult
KW  - Cerebral Arteries: diagnostic imaging
KW  - Cerebral Arteries: anatomy & histology
KW  - Image Processing, Computer-Assisted
KW  - Middle Aged
KW  - high‐resolution imaging (Other)
KW  - inter‐individual vascular variability (Other)
KW  - motor cortex vascularization (Other)
KW  - ultra‐high field (Other)
KW  - vessel atlas (Other)
KW  - vessel dominance (Other)
KW  - vessel supply patterns (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40762423
C2  - pmc:PMC12322923
DO  - DOI:10.1002/hbm.70311
UR  - https://pub.dzne.de/record/280227
ER  -