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@ARTICLE{Ye:280287,
      author       = {Ye, Lan and Greten, Stephan and Wilkens, Ida and Wegner,
                      Florian and Krey, Lea and Höllerhage, Matthias and
                      Pötter-Nerger, Monika and Zeitzschel, Molly and Hagena,
                      Keno and Kassubek, Jan and Süß, Patrick and Winkler,
                      Jürgen and Berg, Daniela and Paschen, Steffen and Tönges,
                      Lars and Gruber, Doreen and Gandor, Florin and Jost,
                      Wolfgang H and Kühn, Andrea A and Claus, Inga and Warnecke,
                      Tobias and Pedrosa, David J and Eggers, Carsten and
                      Trenkwalder, Claudia and Classen, Joseph and Schwarz,
                      Johannes and Schnitzler, Alfons and Höglinger, Günter and
                      Klietz, Martin},
      title        = {{T}ackling gender in progressive supranuclear palsy: {M}ale
                      patients present more apathy.},
      journal      = {Journal of Parkinson's Disease},
      volume       = {15},
      number       = {5},
      issn         = {1877-7171},
      address      = {Amsterdam},
      publisher    = {IOS Press},
      reportid     = {DZNE-2025-00942},
      pages        = {1024 - 1028},
      year         = {2025},
      abstract     = {Gender differences in progressive supranuclear palsy (PSP)
                      may become relevant for clinical trials, treatment decisions
                      and patient counseling. To study gender associated
                      differences we conducted a retrospective data analysis of
                      191 male and 157 female PSP patients from a large
                      multicenter observational cohort in Germany. While no
                      differences in motor skills, disease severity, daily living
                      abilities, global cognitive status and depressive symptoms
                      were observed between genders, male patients showed
                      significantly higher apathy scores, a finding also noted in
                      other neurological diseases. In this study, apart from male
                      patients exhibiting higher levels of apathy, no significant
                      disease-specific gender differences were observed in PSP
                      patients.},
      keywords     = {Humans / Supranuclear Palsy, Progressive: physiopathology /
                      Supranuclear Palsy, Progressive: psychology / Supranuclear
                      Palsy, Progressive: complications / Male / Apathy:
                      physiology / Female / Aged / Retrospective Studies / Middle
                      Aged / Sex Factors / Severity of Illness Index / Germany /
                      Aged, 80 and over / Depression: etiology / apathy (Other) /
                      gender (Other) / progressive supranuclear palsy (Other)},
      cin          = {Clinical Study Center (Ulm) / AG Kühn},
      ddc          = {610},
      cid          = {I:(DE-2719)5000077 / I:(DE-2719)5000008},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40462618},
      doi          = {10.1177/1877718X251343094},
      url          = {https://pub.dzne.de/record/280287},
}