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@MISC{Knab:280741,
author = {Knab, Felix and Koch, Stefan Paul and Major, Sebastian and
Farr, Tracy D. and Mueller, Susanne and Euskirchen, Philipp
and Eggers, Moritz and Kuffner, Melanie T. C. and Walter,
Josefine and Dreier, Jens P. and Endres, Matthias and
Dirnagl, Ulrich and Wenger, Nikolaus and Hoffmann, Christian
J. and Boehm-Sturm, Philipp and Harms, Christoph},
title = {{O}pen data repository, {K}nab et al., {P}rediction of
stroke outcome in mice based on non-invasive {MRI} and
behavioral testing},
publisher = {Zenodo},
reportid = {DZNE-2025-00962},
year = {2022},
abstract = {Open data repository, Knab et al., Prediction of stroke
outcome in mice based on non-invasive MRI and behavioral
testing Open data repository Knab et al. Prediction of
stroke outcome in mice based on non-invasvive MRI and
behavioral testing Content: README.txt This information dat
Contains MRI data in NIFTI format and secondary data from
atlas registration. For documentation of atlas registration
files see https://pubmed.ncbi.nlm.nih.gov/28829217/ Files
used for the manuscript: t2.nii: t2 weighted image acquired
24 h post stroke masklesion.nii: manually delineated lesion
$ix_ANO.nii:$ Allen brain atlas in native space (i.e.
matching t2.nii) Overlap of regions defined by $ix_ANO.nii$
with masklesion.nii were used for calculating percent damage
in each atlas region $prediction_models$ Contains separated
training and test data as xlsx and csv files with lesion
volumes in cubic mm of the Allen brain atlas space, percent
damage per atlas region and behavioral data. The training
data was used as input for training prediction models in
MATLAB, the results were created using the test data. The
files have following sturcture: Column 1: animal ID Columns
2-537: MRI regions (column title corresponds to the region
number as used in the Allen common coordinate framework)
Column 538: lesion volume Column 539: initial performance
(subacute deficit) = mean performance/deficit on days 2-6
Column 540: mean performance/deficit on days 2-6 = initial
performance (subacute deficit) - this column equals column
539 but has different header which was used to train the
residual from initial deficit Column 541: residual
performance/deficit Column 542: test or training group
Consecutive rows contain data for each animal specified by
the animal id The repository also contains all trained
models, prediction results for the test data and tables with
resulting median absolute error (MedAE) and 5th, 25th, 75th
and 95 absolute error quantiles for each model. The model
files end with $'_models.mat'$ and contain 50 independently
trained models each. Each model version is specified by
number 1-50. The result files end with $'_test_results.mat'$
or $'_test_results.xlsx',$ files with MedAE and quantiles
end with $'_test_errors.xlsx'$ or $'_test_errors.csv.$ The
common part of filenames specifies the used paradigm Folder
'subacute deficit prediction' contains: -
$initial_performance_from_lesion_volume:$ prediction of
subacute deficit using lesion volume -
$initial_performance_from_segmented_mri:$ prediction of
subacute deficit using segmented mri Folder 'long-term
outcome prediction' contains: - $lesion_volume:$ prediction
of residual deficit using lesion volume - $segmented_mri:$
prediction of residual deficit using $segmented_mri$ -
$initial_performance:$ prediction of residual deficit using
subacute deficit Folder $'mri_inc_oob_imp'$ contains models
trained using increasing number of mri segments sorted
according to the out-of-bag importance. The number of used
segments is given in the file name. The models, results and
errors are separated in subfolders. Files with equal file
name and different extension always contain the same data},
keywords = {stroke (Other) / mice (Other) / outcome prediction (Other)
/ motor-function (Other) / staircase (Other)},
cin = {AG Endres / AG Dirnagl},
cid = {I:(DE-2719)1811005 / I:(DE-2719)1810002},
pnm = {353 - Clinical and Health Care Research (POF4-353)},
pid = {G:(DE-HGF)POF4-353},
typ = {PUB:(DE-HGF)32},
doi = {10.5281/zenodo.6534691},
url = {https://pub.dzne.de/record/280741},
}