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000280743 1001_ $$00000-0003-4017-6505$$aAlberti, Simon$$b0
000280743 245__ $$aCurrent practices in the study of biomolecular condensates: a community comment.
000280743 260__ $$a[London]$$bSpringer Nature$$c2025
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000280743 520__ $$a The realization that the cell is abundantly compartmentalized into biomolecular condensates has opened new opportunities for understanding the physics and chemistry underlying many cellular processes, fundamentally changing the study of biology. The term biomolecular condensate refers to non-stoichiometric assemblies that are composed of multiple types of macromolecules in cells, occur through phase transitions, and can be investigated by using concepts from soft matter physics. As such, they are intimately related to aqueous two-phase systems and water-in-water emulsions. Condensates possess tunable emergent properties such as interfaces, interfacial tension, viscoelasticity, network structure, dielectric permittivity, and sometimes interphase pH gradients and electric potentials–. They can form spontaneously in response to specific cellular conditions or to active processes, and cells appear to have mechanisms to control their size and location–. Importantly, in contrast to membrane-enclosed organelles such as mitochondria or peroxisomes, condensates do not require the presence of a surrounding membrane.
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000280743 7001_ $$00000-0002-7893-3543$$aBest, Robert B$$b2
000280743 7001_ $$00000-0002-9705-9871$$aBoeynaems, Steven$$b3
000280743 7001_ $$00000-0003-1623-5077$$aCai, Danfeng$$b4
000280743 7001_ $$aCollepardo-Guevara, Rosana$$b5
000280743 7001_ $$aDignon, Gregory L$$b6
000280743 7001_ $$00000-0002-3872-8502$$aDimova, Rumiana$$b7
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000280743 7001_ $$00000-0003-1242-9958$$aMukhopadhyay, Samrat$$b21
000280743 7001_ $$00000-0001-9098-3423$$aMyong, Sua$$b22
000280743 7001_ $$00000-0003-2568-1378$$aPappu, Rohit V$$b23
000280743 7001_ $$00000-0001-9951-9395$$aRippe, Karsten$$b24
000280743 7001_ $$00000-0003-1367-5309$$aShelkovnikova, Tatyana A$$b25
000280743 7001_ $$00000-0002-6198-3245$$aVecchiarelli, Anthony G$$b26
000280743 7001_ $$0P:(DE-2719)2812695$$aWegmann, Susanne$$b27
000280743 7001_ $$00000-0002-1784-2664$$aZhang, Huaiying$$b28
000280743 7001_ $$00000-0001-9404-0190$$aZhang, Mingjie$$b29
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000280743 773__ $$0PERI:(DE-600)2553671-0$$a10.1038/s41467-025-62055-8$$gVol. 16, no. 1, p. 7730$$n1$$p7730$$tNature Communications$$v16$$x2041-1723$$y2025
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