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@INBOOK{PanMontojo:280933,
      author       = {Pan-Montojo, F. and Löwenbrück, Kai and Reichmann, H.},
      title        = {{T}he role of environmental toxins and inflammation in
                      {P}arkinson's disease pathophysiology: a historical
                      perspective and research-based evidence},
      publisher    = {Elsevier},
      reportid     = {DZNE-2025-01016},
      pages        = {29 - 55},
      year         = {2020},
      comment      = {Diagnosis and Management in Parkinson's Disease /
                      Pan-Montojo, F. ; : Elsevier, 2020, ; ISBN: 9780128159460 ;
                      doi:10.1016/B978-0-12-815946-0.00003-X},
      booktitle     = {Diagnosis and Management in
                       Parkinson's Disease / Pan-Montojo, F. ;
                       : Elsevier, 2020, ; ISBN: 9780128159460
                       ;
                       doi:10.1016/B978-0-12-815946-0.00003-X},
      abstract     = {Parkinson's disease (PD) was first described by the English
                      physician James Parkinson in his work An Essay on the
                      Shaking Palsy in 1817. This correlates well with the
                      beginning of the industrial and chemical revolution in
                      Europe during the late 18th and 19th centuries. This period
                      and the time afterward are linked to the increased
                      production and use of chemicals and pesticides. In this
                      chapter, we review (1) the epidemiological evidence linking
                      the appearance of PD to an increase in exposure to
                      environmental toxins, and (2) the possible mechanisms
                      underlying this correlation obtained from in vitro and in
                      vivo experimental studies.},
      cin          = {AG Falkenburger},
      cid          = {I:(DE-2719)1710012},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)7},
      doi          = {10.1016/B978-0-12-815946-0.00003-X},
      url          = {https://pub.dzne.de/record/280933},
}