000280934 001__ 280934 000280934 005__ 20250918102642.0 000280934 037__ $$aDZNE-2025-01017 000280934 1001_ $$0P:(DE-2719)9001205$$aHerholz, Karl$$b0 000280934 245__ $$aFunctional and Molecular Neuroimaging 000280934 260__ $$bElsevier$$c2021 000280934 29510 $$aBradley and Daroff's Neurology in Clinical Practice 000280934 300__ $$a576 - 600.e10 000280934 3367_ $$2ORCID$$aBOOK_CHAPTER 000280934 3367_ $$07$$2EndNote$$aBook Section 000280934 3367_ $$2DRIVER$$abookPart 000280934 3367_ $$2BibTeX$$aINBOOK 000280934 3367_ $$2DataCite$$aOutput Types/Book chapter 000280934 3367_ $$0PUB:(DE-HGF)7$$2PUB:(DE-HGF)$$aContribution to a book$$bcontb$$mcontb$$s1758103396_31852 000280934 4900_ $$v1 000280934 520__ $$aThis chapter provides an overview on the diagnostic utility of positron emission tomography (PET), single-photon emission computed tomography (SPECT), and functional magnetic resonance imaging (fMRI) in neurology. PET is now providing essential imaging biomarkers for Alzheimer disease (AD), especially for its early detection and differentiation from other neurodegenerative diseases such as frontotemporal dementia (FTD) and dementia with Lewy bodies (DLB). PET and SPECT also play important roles for the diagnosis of Parkinson disease, focal epilepsy, paraneoplastic encephalitis, and coma. PET can demonstrate metabolic activity of brain tumors and contribute to therapy planning and early detection of recurrent tumors. Increasingly, fMRI, which is still primarily a tool for research, may also support diagnosis of neurodegenerative diseases, focal epilepsy, and recovery after ischemic stroke. fMRI is also used for the presurgical localization of motor and language function. 000280934 536__ $$0G:(DE-HGF)POF4-353$$a353 - Clinical and Health Care Research (POF4-353)$$cPOF4-353$$fPOF IV$$x0 000280934 588__ $$aDataset connected to DataCite 000280934 7001_ $$0P:(DE-2719)2000026$$aTeipel, Stefan$$b1$$udzne 000280934 7001_ $$0P:(DE-HGF)0$$aHellwig, Sabine$$b2 000280934 7001_ $$0P:(DE-HGF)0$$aLangner, Sönke$$b3 000280934 7001_ $$0P:(DE-HGF)0$$aRijntjes, Michel$$b4 000280934 7001_ $$0P:(DE-2719)9002559$$aKlöppel, Stefan$$b5 000280934 7001_ $$0P:(DE-HGF)0$$aWeiller, Cornelius$$b6 000280934 7001_ $$0P:(DE-HGF)0$$aMeyer, Philipp T.$$b7 000280934 909CO $$ooai:pub.dzne.de:280934$$pVDB 000280934 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2000026$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b1$$kDZNE 000280934 9131_ $$0G:(DE-HGF)POF4-353$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vClinical and Health Care Research$$x0 000280934 9201_ $$0I:(DE-2719)1510100$$kAG Teipel$$lClinical Dementia Research (Rostock /Greifswald)$$x0 000280934 980__ $$acontb 000280934 980__ $$aVDB 000280934 980__ $$aI:(DE-2719)1510100 000280934 980__ $$aUNRESTRICTED