%0 Journal Article
%A Glaeser, Eva
%A Kilimann, Ingo
%A Platen, Moritz
%A Hoffmann, Wolfgang
%A Brosseron, Frederic
%A Buerger, Katharina
%A Coenjaerts, Marie
%A Düzel, Emrah
%A Ewers, Michael
%A Fliessbach, Klaus
%A Frommann, Ingo
%A Gemenetzi, Maria
%A Glanz, Wenzel
%A Hellmann-Regen, Julian
%A Incesoy, Enise I
%A Janowitz, Daniel
%A Jessen, Frank
%A Peters, Oliver
%A Priller, Josef
%A Ramirez, Alfredo
%A Schneider, Anja
%A Spottke, Annika
%A Spruth, Eike Jakob
%A Teipel, Stefan
%A Wagner, Michael
%A Michalowsky, Bernhard
%T The economic burden of subjective cognitive decline, mild cognitive impairment and Alzheimer's dementia: excess costs and associated clinical and risk factors.
%J Alzheimer's research & therapy
%V 17
%N 1
%@ 1758-9193
%C London
%I BioMed Central
%M DZNE-2025-01034
%P 142
%D 2025
%X With the availability of first disease-modifying treatments, evidence on costs across the entire Alzheimer's Continuum, especially for early disease stages, becomes increasingly important to inform healthcare planning, resource allocation, and policy decisions. This study assessed costs and cost-associated factors in patients with subjective cognitive decline (SCD), mild cognitive impairment (MCI) and Alzheimer's Disease (AD) dementia compared to healthy controls.The German DELCODE cohort study assessed clinical data, healthcare resource use, and informal care provision. Costs were calculated from payer and societal perspectives using standardized unit costs, and multivariate regression analyses identified cost-associated factors.From a payer perspective, costs were elevated by 26
%K Humans
%K Cognitive Dysfunction: economics
%K Cognitive Dysfunction: epidemiology
%K Cognitive Dysfunction: therapy
%K Male
%K Female
%K Alzheimer Disease: economics
%K Alzheimer Disease: epidemiology
%K Alzheimer Disease: therapy
%K Aged
%K Cost of Illness
%K Risk Factors
%K Health Care Costs
%K Aged, 80 and over
%K Germany: epidemiology
%K Cohort Studies
%K Middle Aged
%K Alzheimer’s disease (Other)
%K Apolipoprotein E (Other)
%K Cognition (Other)
%K Cost (Other)
%K Dementia (Other)
%K Economics (Other)
%K Mild cognitive impairment (Other)
%K Subjective cognitive decline (Other)
%K Utilization (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40571933
%2 pmc:PMC12199487
%R 10.1186/s13195-025-01785-9
%U https://pub.dzne.de/record/280952