TY  - JOUR
AU  - Glaeser, Eva
AU  - Kilimann, Ingo
AU  - Platen, Moritz
AU  - Hoffmann, Wolfgang
AU  - Brosseron, Frederic
AU  - Buerger, Katharina
AU  - Coenjaerts, Marie
AU  - Düzel, Emrah
AU  - Ewers, Michael
AU  - Fliessbach, Klaus
AU  - Frommann, Ingo
AU  - Gemenetzi, Maria
AU  - Glanz, Wenzel
AU  - Hellmann-Regen, Julian
AU  - Incesoy, Enise I
AU  - Janowitz, Daniel
AU  - Jessen, Frank
AU  - Peters, Oliver
AU  - Priller, Josef
AU  - Ramirez, Alfredo
AU  - Schneider, Anja
AU  - Spottke, Annika
AU  - Spruth, Eike Jakob
AU  - Teipel, Stefan
AU  - Wagner, Michael
AU  - Michalowsky, Bernhard
TI  - The economic burden of subjective cognitive decline, mild cognitive impairment and Alzheimer's dementia: excess costs and associated clinical and risk factors.
JO  - Alzheimer's research & therapy
VL  - 17
IS  - 1
SN  - 1758-9193
CY  - London
PB  - BioMed Central
M1  - DZNE-2025-01034
SP  - 142
PY  - 2025
AB  - With the availability of first disease-modifying treatments, evidence on costs across the entire Alzheimer's Continuum, especially for early disease stages, becomes increasingly important to inform healthcare planning, resource allocation, and policy decisions. This study assessed costs and cost-associated factors in patients with subjective cognitive decline (SCD), mild cognitive impairment (MCI) and Alzheimer's Disease (AD) dementia compared to healthy controls.The German DELCODE cohort study assessed clinical data, healthcare resource use, and informal care provision. Costs were calculated from payer and societal perspectives using standardized unit costs, and multivariate regression analyses identified cost-associated factors.From a payer perspective, costs were elevated by 26
KW  - Humans
KW  - Cognitive Dysfunction: economics
KW  - Cognitive Dysfunction: epidemiology
KW  - Cognitive Dysfunction: therapy
KW  - Male
KW  - Female
KW  - Alzheimer Disease: economics
KW  - Alzheimer Disease: epidemiology
KW  - Alzheimer Disease: therapy
KW  - Aged
KW  - Cost of Illness
KW  - Risk Factors
KW  - Health Care Costs
KW  - Aged, 80 and over
KW  - Germany: epidemiology
KW  - Cohort Studies
KW  - Middle Aged
KW  - Alzheimer’s disease (Other)
KW  - Apolipoprotein E (Other)
KW  - Cognition (Other)
KW  - Cost (Other)
KW  - Dementia (Other)
KW  - Economics (Other)
KW  - Mild cognitive impairment (Other)
KW  - Subjective cognitive decline (Other)
KW  - Utilization (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40571933
C2  - pmc:PMC12199487
DO  - DOI:10.1186/s13195-025-01785-9
UR  - https://pub.dzne.de/record/280952
ER  -