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@ARTICLE{Lehmann:280967,
      author       = {Lehmann, Johannes and Catanese, Alberto},
      title        = {{SYT}13: {A}n underestimated synaptotagmin.},
      journal      = {Biochimica et biophysica acta / Molecular cell research},
      volume       = {1872},
      number       = {8},
      issn         = {0167-4889},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {DZNE-2025-01049},
      pages        = {120031},
      year         = {2025},
      abstract     = {Synaptotagmin-13 (SYT13) is a non-canonical member of the
                      of synaptotagmin family that, canonical synaptotagmins,
                      doesn't contain Ca2+ binding sites, but still appears to
                      play a key role in the control of different cellular
                      processes such as vesicle transport, cell migration,
                      signaling and cell development. The recent findings
                      associate SYT13 with neuronal survival and development,
                      metabolic homeostasis (especially insulin secretion) and
                      both oncogenic and tumor suppressive function in multiple
                      cancers. And yet all this data is scattered in fields, with
                      no systematic review covering SYT13's detailed biology. A
                      comprehensive literature review is therefore needed to
                      explain SYT13's multifaceted roles, uncover informational
                      gaps and direct future studies to exploit SYT13 as a target
                      for neurodegeneration, metabolic disease and cancer
                      therapy.},
      subtyp        = {Review Article},
      keywords     = {SYT13 (Other) / Synaptotagmin (Other) / Synaptotagmin13
                      (Other) / Syt XIII (Other)},
      cin          = {AG Böckers},
      ddc          = {570},
      cid          = {I:(DE-2719)1910002},
      pnm          = {352 - Disease Mechanisms (POF4-352)},
      pid          = {G:(DE-HGF)POF4-352},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40749746},
      doi          = {10.1016/j.bbamcr.2025.120031},
      url          = {https://pub.dzne.de/record/280967},
}