%0 Journal Article
%A Arndt, Philipp
%A Boewe, Stefanie
%A Brüggemann, Jascha
%A Garcia-Garcia, Berta
%A Yakupov, Renat
%A Vockert, Niklas
%A Maas, Anne
%A Pfister, Malte
%A Perosa, Valentina
%A Dubai, Marwa Al
%A Jansen, Robin
%A Meuth, Sven G
%A Dörner, Marc
%A Müller, Patrick
%A Henneicke, Solveig
%A Schreiber, Frank
%A Neumann, Katja
%A Mattern, Hendrik
%A Schreiber, Stefanie
%T Putamen vascularization on high-resolution 7T MRI is associated with perfusion and cognitive performance in cerebral small vessel disease.
%J NeuroImage
%V 319
%@ 1053-8119
%C Orlando, Fla.
%I Academic Press
%M DZNE-2025-01053
%P 121426
%D 2025
%X In cerebral small vessel disease (CSVD), compromised arterial supply to the deep gray matter contributes to cognitive decline. While CSVD frequently involves lenticulostriate arteries supplying the putamen, the functional consequences of altered putaminal vascular architecture remain unclear. We hypothesized that a less homogeneous arterial network in the putamen is associated with impaired perfusion and worse cognitive performance in CSVD.We enrolled 16 CSVD patients with cerebral microbleeds and 21 age‑matched controls (mean age 71 years; 38 
%K Humans
%K Female
%K Aged
%K Male
%K Cerebral Small Vessel Diseases: diagnostic imaging
%K Cerebral Small Vessel Diseases: physiopathology
%K Cerebral Small Vessel Diseases: complications
%K Putamen: blood supply
%K Putamen: diagnostic imaging
%K Putamen: physiopathology
%K Middle Aged
%K Magnetic Resonance Imaging: methods
%K Cerebrovascular Circulation: physiology
%K Cognitive Dysfunction: diagnostic imaging
%K Cognitive Dysfunction: physiopathology
%K Cognitive Dysfunction: etiology
%K Cognition: physiology
%K Aged, 80 and over
%K Arterial spin labelling (Other)
%K Basal ganglia (Other)
%K Cerebral small vessel disease (Other)
%K Cognition (Other)
%K Lenticulostriate arteries (Other)
%K Putamen (Other)
%K Vessel distance mapping (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40850635
%R 10.1016/j.neuroimage.2025.121426
%U https://pub.dzne.de/record/280971