guest ::
| Home > Publications Database > Association of Lipoprotein(a) With Cardiovascular and Cerebrovascular Disease in a Nationally Representative Cohort of Germany. > print |
| Home > Publications Database > Association of Lipoprotein(a) With Cardiovascular and Cerebrovascular Disease in a Nationally Representative Cohort of Germany. > print |
| 001 | 280976 | ||
| 005 | 20250921002019.0 | ||
| 024 | 7 | _ | |a 10.1016/j.jacadv.2025.102015 |2 doi |
| 024 | 7 | _ | |a pmid:40706144 |2 pmid |
| 024 | 7 | _ | |a pmc:PMC12309279 |2 pmc |
| 024 | 7 | _ | |a altmetric:179704956 |2 altmetric |
| 037 | _ | _ | |a DZNE-2025-01058 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Gelfert, Gloria G |b 0 |
| 245 | _ | _ | |a Association of Lipoprotein(a) With Cardiovascular and Cerebrovascular Disease in a Nationally Representative Cohort of Germany. |
| 260 | _ | _ | |a [Amsterdam] |c 2025 |b Elsevier B.V. |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1758110381_31850 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a Population-based data on the distribution of lipoprotein(a) (Lp[a]) within the German population are lacking.The aim of the study was to determine the age- and sex-specific Lp(a) distribution in Germany and analyze its association with different types of cardiovascular disease (CVD).We analyzed cross-sectional data from the German National Health Interview and Examination Survey 1998, a population-based study representing the German adult population's health status from 1997 to 1999. We examined serum Lp(a) according to demographics and investigated associations between Lp(a) and history of self-reported CVD. We tested Lp(a) in spline analysis on continuous scales and as dichotomous Lp(a) thresholds.In the German National Health Interview and Examination Survey 1998 (n = 6,657), median Lp(a) was 15.3 mg/dL (Q1-Q3: 5.6, 43.1). Lp(a) levels ≥50 mg/dL were present in 21.6%. Men had substantially higher median Lp(a) than women (22.1 mg/dL vs 10.3 mg/dL). Median Lp(a) levels were significantly higher in individuals with than without a history of atherosclerotic cardiovascular disease (ASCVD) but did not significantly differ between people with and without venous thrombosis. In logistic regression analysis with splines, higher Lp(a) levels were associated with a higher probability of a history of CVD. In logistic regression analyses, Lp(a) ≥50 mg/dL was associated with a history of ASCVD (OR: 1.36 [95% CI: 1.04-1.78]; P = 0.023).About 1 in 5 German individuals from a prestatin era population had Lp(a) levels ≥50 mg/dL. Higher levels were independently associated with ASCVD, but not with venous thrombosis. These findings provide a basis for future prospective studies to define the role of Lp(a) in CVD risk in the German population. |
| 536 | _ | _ | |a 353 - Clinical and Health Care Research (POF4-353) |0 G:(DE-HGF)POF4-353 |c POF4-353 |f POF IV |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, , Journals: pub.dzne.de |
| 650 | _ | 7 | |a cardiovascular disease |2 Other |
| 650 | _ | 7 | |a cardiovascular risk |2 Other |
| 650 | _ | 7 | |a epidemiology |2 Other |
| 650 | _ | 7 | |a lipoprotein(a) |2 Other |
| 650 | _ | 7 | |a prevention |2 Other |
| 650 | _ | 7 | |a venous thrombosis |2 Other |
| 700 | 1 | _ | |a Grittner, Ulrike |b 1 |
| 700 | 1 | _ | |a Kuhnert, Ronny |b 2 |
| 700 | 1 | _ | |a Scheidt-Nave, Christa |b 3 |
| 700 | 1 | _ | |a Endres, Matthias |0 P:(DE-2719)2811033 |b 4 |u dzne |
| 700 | 1 | _ | |a Nave, Alexander H |b 5 |
| 773 | _ | _ | |a 10.1016/j.jacadv.2025.102015 |g Vol. 4, no. 8, p. 102015 - |0 PERI:(DE-600)3169577-2 |n 8 |p 102015 |t JACC: advances |v 4 |y 2025 |x 2772-963X |
| 856 | 4 | _ | |u https://pub.dzne.de/record/280976/files/DZNE-2025-01058%20SUP.pdf |
| 856 | 4 | _ | |u https://pub.dzne.de/record/280976/files/DZNE-2025-01058.pdf |y Restricted |
| 856 | 4 | _ | |u https://pub.dzne.de/record/280976/files/DZNE-2025-01058%20SUP.pdf?subformat=pdfa |x pdfa |
| 856 | 4 | _ | |u https://pub.dzne.de/record/280976/files/DZNE-2025-01058.pdf?subformat=pdfa |x pdfa |y Restricted |
| 909 | C | O | |o oai:pub.dzne.de:280976 |p VDB |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 4 |6 P:(DE-2719)2811033 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Neurodegenerative Diseases |1 G:(DE-HGF)POF4-350 |0 G:(DE-HGF)POF4-353 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-300 |4 G:(DE-HGF)POF |v Clinical and Health Care Research |x 0 |
| 914 | 1 | _ | |y 2025 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |d 2025-01-02 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2025-01-02 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0501 |2 StatID |b DOAJ Seal |d 2024-03-22T12:36:56Z |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0500 |2 StatID |b DOAJ |d 2024-03-22T12:36:56Z |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b DOAJ : Anonymous peer review |d 2024-03-22T12:36:56Z |
| 915 | _ | _ | |a Article Processing Charges |0 StatID:(DE-HGF)0561 |2 StatID |d 2025-01-02 |
| 915 | _ | _ | |a Fees |0 StatID:(DE-HGF)0700 |2 StatID |d 2025-01-02 |
| 920 | 1 | _ | |0 I:(DE-2719)1811005 |k AG Endres |l Interdisciplinary Dementia Research |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-2719)1811005 |
| 980 | _ | _ | |a UNRESTRICTED |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|