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@ARTICLE{Montesinos:281108,
author = {Montesinos, Ricardo Paricio and Gründemann, Jan},
title = {{S}ensory thalamus function, plasticity and neuromodulation
in health and disease},
journal = {Brain research bulletin},
volume = {230},
issn = {0361-9230},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {DZNE-2025-01069},
pages = {111508},
year = {2025},
abstract = {For each of the many sensory channels through which animals
perceive the world, sensory thalamus is an important
processing station whose role lies between faithful stimulus
encoding and cognitive interpretation. Located deep in the
brain, sensory thalamus neurons must receive and transmit
peripheral information reliably, while modulating it based
on valence, internal states and memory from previous
experience. It has to speak to the neocortex with the
appropriate volume, and in an orderly way, to prioritize
attention to what matters most in each circumstance. In this
review, we recapitulate classic and recent findings on the
sensory thalamus, and how its plasticity and modulation
allow it to provide a basis not only for perception, but
also memory and cognition. Finally, we discuss how
alterations in sensory thalamus may underlie pathogenesis or
contribute to specific symptoms of cognitive and
neuropsychiatric disorders.},
subtyp = {Review Article},
keywords = {Disease (Other) / Learning (Other) / Neuromodulation
(Other) / Sensory (Other) / TRN (Other) / Thalamus (Other)},
cin = {AG Gründemann},
ddc = {150},
cid = {I:(DE-2719)5000069},
pnm = {351 - Brain Function (POF4-351)},
pid = {G:(DE-HGF)POF4-351},
typ = {PUB:(DE-HGF)16},
doi = {10.1016/j.brainresbull.2025.111508},
url = {https://pub.dzne.de/record/281108},
}