TY - JOUR
AU - Beckmann, Janna
AU - Petzold, Moritz
AU - Betzler, Felix
AU - Ströhle, Andreas
AU - Bendau, Antonia
AU - Dusemund, Carla
AU - Petzold, Gabor C
AU - Meisel, Andreas
AU - Hoffmann, Sarah
TI - Anxiety in Myasthenia Gravis Patients Throughout the COVID-19 Pandemic-Prevalence, Risk Factors, and Association With Vaccination Status.
JO - Brain and behavior
VL - 15
IS - 9
SN - 2162-3279
CY - Malden, Mass.
PB - Wiley
M1 - DZNE-2025-01099
SP - e70878
PY - 2025
AB - A high prevalence of COVID-19-related anxiety was observed among the general population during the COVID-19 pandemic. Patients with myasthenia gravis (MG) might be at higher risk for COVID-19-related anxiety due to immunosuppressive therapy in the majority of cases and risk of myasthenic exacerbation in case of an infection. This prospective longitudinal study assessed COVID-19-related anxiety in MG patients over 2 years of the pandemic and its association with MG-specific factors (e.g., disease severity, immunosuppressive medication) and with vaccination status.A three-wave longitudinal online survey was conducted from May 2020 to February 2022, including a total of 648 adult MG patients. Descriptive, univariate, and multivariate analyses were performed to assess COVID-19-related and MG-related anxiety, associated MG-specific factors, and association with vaccination status.COVID-19-related anxiety was frequent, with the most pronounced fear being risk for one's own health (overall 83.9
KW - Humans
KW - Myasthenia Gravis: psychology
KW - Myasthenia Gravis: epidemiology
KW - Myasthenia Gravis: drug therapy
KW - Myasthenia Gravis: complications
KW - COVID-19: psychology
KW - COVID-19: epidemiology
KW - Female
KW - Male
KW - Anxiety: epidemiology
KW - Anxiety: etiology
KW - Anxiety: psychology
KW - Middle Aged
KW - Risk Factors
KW - Prevalence
KW - Adult
KW - Aged
KW - Longitudinal Studies
KW - Prospective Studies
KW - Vaccination: psychology
KW - Vaccination: statistics & numerical data
KW - Immunosuppressive Agents: therapeutic use
KW - Immunosuppressive Agents: adverse effects
KW - SARS-CoV-2
KW - autoimmune disease (Other)
KW - corona (Other)
KW - fear (Other)
KW - immunosuppressive treatment (Other)
KW - Immunosuppressive Agents (NLM Chemicals)
LB - PUB:(DE-HGF)16
C6 - pmid:40958409
C2 - pmc:PMC12441002
DO - DOI:10.1002/brb3.70878
UR - https://pub.dzne.de/record/281352
ER -