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000281526 037__ $$aDZNE-2025-01144
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000281526 1001_ $$aTebartz van Elst, Ludger$$b0
000281526 245__ $$aThe Neuropsychiatric Checklist for Autoimmune Psychosis: A Narrative Review.
000281526 260__ $$aAmsterdam [u.a.]$$bElsevier Science$$c2025
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000281526 520__ $$aAutoimmune encephalitis (AE) is a rapidly evolving topic in both neurology and psychiatry. A recent international consensus article defined criteria for possible, probable, and definite autoimmune psychosis (AP) inspired by the principles established in neurology for the definition of AE. This has stimulated much clinical research on AP but also criticism of the validity of the criteria for possible AP, justifying additional clinical investigations such as lumbar puncture. In clinical practice, it is often difficult to decide how far diagnostic procedures such as lumbar punctures and immunotherapies should go in unclear cases. Against this background, we have 3 aims in this review. First, we summarize and compare the available concepts for the diagnosis of AP in a systematic literature review. Second, we present an overview of typical specific and nonspecific findings that can be obtained in laboratory, electroencephalography, magnetic resonance imaging, cerebrospinal fluid, and [18F]fluorodeoxyglucose positron emission tomography studies in the context of AP. Thirdly, we summarize these findings and present the Neuropsychiatric Checklist for Autoimmune Psychosis as a tool for clinical assessment of the likelihood of AP, with reference to the typical red-flag symptoms and the specific and many unspecific findings that can be identified in additional investigations. We suggest that this instrument may be a useful tool for a comprehensive, possibly uniform, and standardized case assessment in the context of possible AP.
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000281526 650_7 $$2Other$$aAutoantibody
000281526 650_7 $$2Other$$aAutoimmune psychiatric symptoms
000281526 650_7 $$2Other$$aAutoimmune psychosis
000281526 650_7 $$2Other$$aDiagnostics
000281526 650_7 $$2Other$$aSchizophrenia
000281526 650_7 $$2Other$$aTherapy
000281526 650_2 $$2MeSH$$aHumans
000281526 650_2 $$2MeSH$$aPsychotic Disorders: diagnosis
000281526 650_2 $$2MeSH$$aPsychotic Disorders: immunology
000281526 650_2 $$2MeSH$$aChecklist
000281526 650_2 $$2MeSH$$aEncephalitis: diagnosis
000281526 650_2 $$2MeSH$$aAutoimmune Diseases: diagnosis
000281526 650_2 $$2MeSH$$aAutoimmune Diseases of the Nervous System: diagnosis
000281526 650_2 $$2MeSH$$aHashimoto Disease: diagnosis
000281526 7001_ $$aRunge, Kimon$$b1
000281526 7001_ $$aMeyer, Philipp T$$b2
000281526 7001_ $$aUrbach, Horst$$b3
000281526 7001_ $$aVenhoff, Nils$$b4
000281526 7001_ $$0P:(DE-2719)2810931$$aPrüss, Harald$$b5$$eLast author$$udzne
000281526 773__ $$0PERI:(DE-600)1499907-9$$a10.1016/j.biopsych.2025.02.889$$gVol. 98, no. 9, p. 654 - 669$$n9$$p654 - 669$$tBiological psychiatry$$v98$$x0006-3223$$y2025
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