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001     281526
005     20251030102704.0
024 7 _ |a 10.1016/j.biopsych.2025.02.889
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037 _ _ |a DZNE-2025-01144
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Tebartz van Elst, Ludger
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245 _ _ |a The Neuropsychiatric Checklist for Autoimmune Psychosis: A Narrative Review.
260 _ _ |a Amsterdam [u.a.]
|c 2025
|b Elsevier Science
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520 _ _ |a Autoimmune encephalitis (AE) is a rapidly evolving topic in both neurology and psychiatry. A recent international consensus article defined criteria for possible, probable, and definite autoimmune psychosis (AP) inspired by the principles established in neurology for the definition of AE. This has stimulated much clinical research on AP but also criticism of the validity of the criteria for possible AP, justifying additional clinical investigations such as lumbar puncture. In clinical practice, it is often difficult to decide how far diagnostic procedures such as lumbar punctures and immunotherapies should go in unclear cases. Against this background, we have 3 aims in this review. First, we summarize and compare the available concepts for the diagnosis of AP in a systematic literature review. Second, we present an overview of typical specific and nonspecific findings that can be obtained in laboratory, electroencephalography, magnetic resonance imaging, cerebrospinal fluid, and [18F]fluorodeoxyglucose positron emission tomography studies in the context of AP. Thirdly, we summarize these findings and present the Neuropsychiatric Checklist for Autoimmune Psychosis as a tool for clinical assessment of the likelihood of AP, with reference to the typical red-flag symptoms and the specific and many unspecific findings that can be identified in additional investigations. We suggest that this instrument may be a useful tool for a comprehensive, possibly uniform, and standardized case assessment in the context of possible AP.
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650 _ 7 |a Autoantibody
|2 Other
650 _ 7 |a Autoimmune psychiatric symptoms
|2 Other
650 _ 7 |a Autoimmune psychosis
|2 Other
650 _ 7 |a Diagnostics
|2 Other
650 _ 7 |a Schizophrenia
|2 Other
650 _ 7 |a Therapy
|2 Other
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Psychotic Disorders: diagnosis
|2 MeSH
650 _ 2 |a Psychotic Disorders: immunology
|2 MeSH
650 _ 2 |a Checklist
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650 _ 2 |a Encephalitis: diagnosis
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650 _ 2 |a Autoimmune Diseases: diagnosis
|2 MeSH
650 _ 2 |a Autoimmune Diseases of the Nervous System: diagnosis
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650 _ 2 |a Hashimoto Disease: diagnosis
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700 1 _ |a Runge, Kimon
|b 1
700 1 _ |a Meyer, Philipp T
|b 2
700 1 _ |a Urbach, Horst
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700 1 _ |a Venhoff, Nils
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700 1 _ |a Prüss, Harald
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773 _ _ |a 10.1016/j.biopsych.2025.02.889
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|t Biological psychiatry
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856 4 _ |u https://pub.dzne.de/record/281526/files/DZNE-2025-01144%20SUP.zip
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