TY  - JOUR
AU  - Špeh, Andreja
AU  - Boada, Merce
AU  - Jessen, Frank
AU  - Visser, Pieter Jelle
AU  - Winblad, Bengt
AU  - Wimo, Anders
AU  - Sannemann, Lena
AU  - Stopar, Nina
AU  - Zwan, Marisa
AU  - Rodriguez-Gomez, Octavio
AU  - Johansson, Gunilla
AU  - Alegret, Montse
AU  - Rodríguez, Isabel
AU  - Gurrutxaga, Miren
AU  - Sotolongo, Oscar
AU  - Ruiz, Agustin
AU  - Cantero-Fortiz, Yahveth
AU  - Kramberger, Milica Gregorič
TI  - Cardiovascular health and cognition in older adults: Variations across recruitment models and European countries in the MOPEAD project.
JO  - Journal of Alzheimer's disease
VL  - 107
IS  - 4
SN  - 1387-2877
CY  - Amsterdam
PB  - IOS Press
M1  - DZNE-2025-01171
SP  - 1530 - 1538
PY  - 2025
AB  - BackgroundThe Models of Patient Engagement for Alzheimer's Disease (MOPEAD) project aimed to identify the most effective and cost-efficient recruitment model for detecting prodromal and mild Alzheimer's disease (AD) across five European countries.ObjectiveTo examine differences in cardiovascular risk factors and cognitive performance among countries and recruitment models using MOPEAD data.MethodsIndividuals aged 65-85 with a high risk for prodromal or mild AD were included. Four recruitment models were used: a web-based screening tool, an open house initiative (OHI), a primary care-based protocol for early detection of cognitive decline, and a tertiary care-based screening at a diabetologist clinic. Participants from Germany, Spain, the Netherlands, Sweden, and Slovenia were recruited. Cardiovascular risk factors were self-reported, and cognition was assessed using The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS).ResultsA total of 414 individuals (mean age 71.9, SD = 5.0) were included. Significant differences were observed in physical activity (p < 0.001), with individuals from Sweden and Slovenia being the most active. Dutch participants scored highest on most cognitive measures. Individuals recruited via web-based survey were youngest, most active (61.7
KW  - Alzheimer's disease (Other)
KW  - cardiovascular health (Other)
KW  - cognition (Other)
KW  - cross-country (Other)
KW  - early diagnosis (Other)
KW  - participants recruitment (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40899930
DO  - DOI:10.1177/13872877251371729
UR  - https://pub.dzne.de/record/281738
ER  -