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@ARTICLE{Akl:282326,
      author       = {Akl, Estelle and Dyrba, Martin and Görß, Doreen and
                      Schumacher, Julia and Weber, Marc-André},
      title        = {{MRI} for diagnosing dementia - update 2025 | {MRT} zur
                      {D}emenzdiagnostik – {U}pdate 2025},
      journal      = {RöFo},
      volume       = {197},
      number       = {12},
      issn         = {1438-9029},
      address      = {Stuttgart [u.a.]},
      publisher    = {Thieme},
      reportid     = {DZNE-2025-01287},
      pages        = {1378 - 1387},
      year         = {2025},
      abstract     = {Magnetic resonance imaging (MRI) plays a crucial role
                      alongside clinical and neuropsychological assessments in
                      diagnosing dementia. The recent and ongoing advancements in
                      MRI technology have significantly enhanced the detection and
                      characterization of the specific neurostructural changes
                      seen in various neurodegenerative diseases, thereby
                      significantly increasing the precision of diagnosis. Within
                      this context of perpetual evolution, this review article
                      explores the recent advances in MRI with regard to
                      diagnosing dementia.A retrospective literature review was
                      conducted by searching the PubMed and ScienceDirect
                      databases for the keywords 'dementia', 'imaging', and 'MRI'.
                      The inclusion criteria were scientific papers in English
                      that revolved around the role of MRI as a diagnostic tool in
                      the field of dementia. A specific time frame was not
                      determined but the focus was on current articles, with an
                      overall of 20 articles dating from the last 6 years (after
                      2018), corresponding to $55\%$ of the total number of
                      articles.This review provides a comprehensive overview of
                      the latest advances in the radiologic diagnosis of dementia
                      using MRI, with a particular focus on the last 6 years.
                      Technical aspects of image acquisition for clinical and
                      research purposes are discussed. MRI findings typical of
                      dementia are described. The findings are divided into
                      non-specific findings of dementia and characteristic
                      findings for certain dementia subtypes. This provides
                      information about possible causes of dementia. In addition,
                      developed scoring systems that support MRI findings are
                      presented, including the MTA score for Alzheimer's disease
                      with corresponding illustrative figures.The symbiosis of
                      clinical evaluation with high-field MRI methodologies
                      enhances dementia diagnosis and offers a holistic and
                      nuanced understanding of structural brain changes associated
                      with dementia and its various subtypes. The latest advances,
                      mainly involving the emergence of ultra-high-field (7T) MRI,
                      despite having limited use in clinical practice, mark a
                      pragmatic shift in the field of research. · High-field MRI
                      (3T) and specialized sequences allow for the detection of
                      early structural changes indicative of dementia.. ·
                      Characteristic neuroanatomical MRI patterns enable the
                      differentiation between various subtypes of dementia.. ·
                      Established scales provide added value to the quantification
                      and categorization of MRI findings in dementia.. · Akl E,
                      Dyrba M, Görß D et al. MRI for diagnosing dementia -
                      update 2024. Rofo 2025; 197: 1378-1387.},
      subtyp        = {Review Article},
      keywords     = {Humans / Magnetic Resonance Imaging: methods / Magnetic
                      Resonance Imaging: trends / Dementia: diagnostic imaging /
                      Brain: diagnostic imaging / Alzheimer Disease: diagnostic
                      imaging / Diagnosis, Differential},
      cin          = {AG Teipel / AG Storch},
      ddc          = {610},
      cid          = {I:(DE-2719)1510100 / I:(DE-2719)5000014},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40209752},
      doi          = {10.1055/a-2563-0725},
      url          = {https://pub.dzne.de/record/282326},
}