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@ARTICLE{vonDanwitz:282587,
      author       = {von Danwitz, Niklas M and Lehnen, Nils C and Meißner,
                      Julius N and Samani, Omid Shirvani and Asperger, Hannah and
                      Thielscher, Christian and Ebrahimi, Taraneh and Layer, Julia
                      and Nitsch, Louisa and Dorn, Franziska and Radbruch,
                      Alexander and Bode, Felix J and Weller, Johannes M and
                      Groteklaes, Anne and Petzold, Gabor C and Sabir, Hemmen and
                      Stösser, Sebastian},
      title        = {{P}ortable ultra-low-field {MRI} in acute stroke care: {A}
                      pilot study.},
      journal      = {European stroke journal},
      volume       = {10},
      number       = {4},
      issn         = {2396-9873},
      address      = {London},
      publisher    = {Sage Publishing},
      reportid     = {DZNE-2025-01347},
      pages        = {1430 - 1437},
      year         = {2025},
      abstract     = {Neuroimaging is a prerequisite for treatment of stroke
                      patients, but it is not available all over the globe.
                      Portable ultra-low field (pULF) MRI has the potential to
                      improve access to neuroimaging and thus stroke care
                      worldwide. In a pilot study, we were the first to utilise
                      pULF-MRI in a European tertiary stroke centre and to
                      evaluate its diagnostic value compared to high-field (HF)
                      MRI.Consecutive patients admitted for suspected ischaemic
                      stroke underwent pULF-MRI using the 0.064 Tesla Swoop®
                      portable MR imaging system in addition to standard imaging.
                      HF-MRI and pULF-MRI scans were blindly assessed to compare
                      the diagnostic accuracy and imaging-based therapeutic
                      decisions based on pULF-MRI to HF-MRI.Seventeen patients
                      underwent pULF-MRI, 12 of whom had ischaemic lesions on
                      HF-MRI. Ischaemic lesions were detected on pULF-MRI in 8/12
                      cases. The four infarcts not identified on pULF-MRI were all
                      smaller than 6 mm in diameter. In all cases, a virtual
                      treatment decision based on pULF-MRI by a blinded team
                      matched the actual clinical decisions.This single-centre
                      study demonstrates that pULF-MRI is a promising tool in
                      acute stroke care, providing reliable imaging for treatment
                      decision and follow-up monitoring. pULF-MRI may support
                      acute stroke care if HF-MRI is unavailable and may be
                      particularly helpful in resource-limited settings.
                      Limitations of pULF-MRI include long acquisition times and
                      the lack of vessel imaging and haemorrhage-sensitive
                      sequences.},
      keywords     = {Humans / Pilot Projects / Male / Female / Aged / Magnetic
                      Resonance Imaging: methods / Magnetic Resonance Imaging:
                      instrumentation / Middle Aged / Aged, 80 and over / Stroke:
                      diagnostic imaging / Ischemic Stroke: diagnostic imaging /
                      Neuroimaging: methods / Neuroimaging: instrumentation /
                      Stroke (Other) / acute care (Other) / emergency department
                      (Other) / health equality (Other) / point of care imaging
                      (Other) / portable ultra-low-field MRI (Other)},
      cin          = {Clinical Research Platform (CRP) / AG Petzold / AG Schultze
                      / Patient Studies (Bonn) / AG Radbruch / AG Sabir},
      ddc          = {610},
      cid          = {I:(DE-2719)1011401 / I:(DE-2719)1013020 /
                      I:(DE-2719)1013038 / I:(DE-2719)1011101 / I:(DE-2719)5000075
                      / I:(DE-2719)5000032},
      pnm          = {353 - Clinical and Health Care Research (POF4-353) / 354 -
                      Disease Prevention and Healthy Aging (POF4-354) / 352 -
                      Disease Mechanisms (POF4-352)},
      pid          = {G:(DE-HGF)POF4-353 / G:(DE-HGF)POF4-354 /
                      G:(DE-HGF)POF4-352},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40515383},
      pmc          = {pmc:PMC12170540},
      doi          = {10.1177/23969873251344761},
      url          = {https://pub.dzne.de/record/282587},
}