000282600 001__ 282600
000282600 005__ 20251211154843.0
000282600 0247_ $$2doi$$a10.1111/jce.70140
000282600 0247_ $$2pmid$$apmid:41078013
000282600 0247_ $$2ISSN$$a1045-3873
000282600 0247_ $$2ISSN$$a0736-6108
000282600 0247_ $$2ISSN$$a0892-1059
000282600 0247_ $$2ISSN$$a1540-8167
000282600 0247_ $$2ISSN$$a2374-8338
000282600 0247_ $$2ISSN$$a2374-8419
000282600 0247_ $$2ISSN$$a2374-8427
000282600 0247_ $$2ISSN$$a8756-9264
000282600 037__ $$aDZNE-2025-01358
000282600 041__ $$aEnglish
000282600 082__ $$a610
000282600 1001_ $$00000-0001-7511-3809$$aSchreiber, Tobias$$b0
000282600 245__ $$aComparison of Cerebral Micro-Embolization Detected by Transcranial Doppler Examination Between Radiofrequency Ablation and Pulsed Field Ablation for Atrial Fibrillation.
000282600 260__ $$aOxford$$bWiley-Blackwell$$c2025
000282600 3367_ $$2DRIVER$$aarticle
000282600 3367_ $$2DataCite$$aOutput Types/Journal article
000282600 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1765464353_17918
000282600 3367_ $$2BibTeX$$aARTICLE
000282600 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000282600 3367_ $$00$$2EndNote$$aJournal Article
000282600 520__ $$aPulsed Field Ablation (PFA) can establish pulmonary vein isolation via irreversible electroporation and is believed to reduce overall complications; however, periprocedural stroke has also been reported after PFA procedures. Assessment of microembolic signals (MES) measured by transcranial doppler (TCD) allows to monitor cerebral embolization during the procedure and to identify higher risk procedural steps. This study was designed to compare the incidence of MES during different procedural steps between two different PFA systems and radiofrequency ablation (RFA).Pulmonary vein isolation was performed either using either high-power short-duration radiofrequency ablation (HPSD RFA), or PFA using a variable loop circular catheter (VLCC) or a circular multielectrode array catheter (CMAC). MES were compared during transseptal puncture, ablation, left atrial mapping, and introduction/retraction of catheters. Neurological examination was performed pre and post ablation for all patients including the National Institutes of Health Stroke Scale (NIHSS). Fifty-six consecutive patients (19 female (34%), average age 70 years) were included: 28 in the HPSD RFA group and 14 patients each in the VLCC and CMAC groups. Total MES count was higher for both PFA systems compared to HPSD RFA (VLCC 1402 (IQR 973), CMAC 449 (IQR 193) vs. HPSD RFA 131 (IQR 250); p < 0.001). MES count was higher in VLCC than in CMAC (p < 0.001). In all groups, MES were most frequently detected during ablation (87% of overall MES). Postprocedural NIHSS did not differ between groups (median NIHSS 0 [IQR 0] in all groups), yet two patients experienced new focal neurological deficits after PFA.Pulsed field ablation was associated with a higher cerebral MES count than high-power short-duration radiofrequency ablation, with marked differences between catheter systems. Transcranial doppler indicates ablation as the most embolic step in both PFA and high-power short duration ablation.
000282600 536__ $$0G:(DE-HGF)POF4-353$$a353 - Clinical and Health Care Research (POF4-353)$$cPOF4-353$$fPOF IV$$x0
000282600 588__ $$aDataset connected to CrossRef, PubMed, , Journals: pub.dzne.de
000282600 650_7 $$2Other$$aatrial fibrillation
000282600 650_7 $$2Other$$amicroembolism
000282600 650_7 $$2Other$$apulsed field ablation
000282600 650_7 $$2Other$$aradiofrequency ablation
000282600 7001_ $$0P:(DE-2719)9001452$$avon Rennenberg, Regina$$b1$$udzne
000282600 7001_ $$aBrämswig, Tim Bastian$$b2
000282600 7001_ $$aLandmesser, Ulf$$b3
000282600 7001_ $$aHindricks, Gerhard$$b4
000282600 7001_ $$aNagel, Patrick$$b5
000282600 7001_ $$aTscholl, Verena$$b6
000282600 7001_ $$aHuemer, Martin$$b7
000282600 7001_ $$aLucas, Johannes$$b8
000282600 7001_ $$aAttanasio, Philipp$$b9
000282600 7001_ $$aNolte, Christian H$$b10
000282600 773__ $$0PERI:(DE-600)2037519-0$$a10.1111/jce.70140$$gVol. 36, no. 12, p. 3288 - 3295$$n12$$p3288 - 3295$$tJournal of cardiovascular electrophysiology$$v36$$x1045-3873$$y2025
000282600 8564_ $$uhttps://pub.dzne.de/record/282600/files/DZNE-2025-01358.pdf$$yRestricted
000282600 8564_ $$uhttps://pub.dzne.de/record/282600/files/DZNE-2025-01358.pdf?subformat=pdfa$$xpdfa$$yRestricted
000282600 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)9001452$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b1$$kDZNE
000282600 9131_ $$0G:(DE-HGF)POF4-353$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vClinical and Health Care Research$$x0
000282600 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz$$d2024-12-28$$wger
000282600 915__ $$0StatID:(DE-HGF)3001$$2StatID$$aDEAL Wiley$$d2024-12-28$$wger
000282600 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2024-12-28
000282600 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bJ CARDIOVASC ELECTR : 2022$$d2024-12-28
000282600 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2024-12-28
000282600 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2024-12-28
000282600 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2024-12-28
000282600 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2024-12-28
000282600 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2024-12-28
000282600 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2024-12-28
000282600 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2024-12-28
000282600 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2024-12-28
000282600 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2024-12-28
000282600 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2024-12-28
000282600 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2024-12-28
000282600 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2024-12-28
000282600 9201_ $$0I:(DE-2719)1811005$$kAG Endres$$lInterdisciplinary Dementia Research$$x0
000282600 980__ $$ajournal
000282600 980__ $$aEDITORS
000282600 980__ $$aVDBINPRINT
000282600 980__ $$aI:(DE-2719)1811005
000282600 980__ $$aUNRESTRICTED