%0 Journal Article
%A Preßler, Hannah
%A Haddy, Imène
%A Daugherty, Claire
%A Postila, Ville
%A Meisel, Andreas
%T Paraneoplastic Lambert-Eaton myasthenic syndrome associated with non-small cell lung cancer: data from the European LEMS registry and systematic review.
%J Neurological research and practice
%V 7
%N 1
%@ 2524-3489
%C [London]
%I BioMed Central
%M DZNE-2025-01362
%P 95
%D 2025
%X Paraneoplastic Lambert-Eaton myasthenic syndrome (pLEMS) is well-established in small-cell lung cancer (SCLC), but data on other malignancies are limited. We aimed to define the clinical phenotype of pLEMS in non-SCLC cancers (non-SCLC-pLEMS) relative to SCLC-associated LEMS (SCLC-pLEMS) and autoimmune LEMS (aiLEMS).Retrospective analysis was conducted to compare patients with SCLC-pLEMS, aiLEMS and non-SCLC-pLEMS from the European LEMS registry, and further non-SCLC-pLEMS cases were identified by a systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.The registry included 72 aiLEMS, 12 SCLC-pLEMS, and 11 non-SCLC-pLEMS patients. LEMS preceded cancer diagnosis in 33
%K Ataxia (Other)
%K Cancer treatment (Other)
%K Lambert-Eaton myasthenic syndrome (Other)
%K Paraneoplastic (Other)
%K Tumor (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:41361909
%2 pmc:PMC12687528
%R 10.1186/s42466-025-00453-5
%U https://pub.dzne.de/record/282604