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@ARTICLE{Sabir:282628,
author = {Sabir, Hemmen},
title = {{N}europrotective therapies for neonatal hypoxic-ischemic
brain injury - a contemporary update.},
journal = {Seminars in perinatology},
volume = {49},
number = {8},
issn = {0146-0005},
address = {Philadelphia, Pa.},
publisher = {Saunders},
reportid = {DZNE-2025-01364},
pages = {152128 -},
year = {2025},
abstract = {Neonatal encephalopathy of hypoxic-ischemic origin remains
a leading cause of global neonatal mortality. Over the past
decades, various neuroprotective strategies have been
explored; however, therapeutic hypothermia remains the only
clinically approved intervention to date. This review
outlines emerging and adjunctive treatment modalities beyond
therapeutic hypothermia and emphasizes the critical need for
robust and reproducible translational research to bridge the
gap between preclinical findings and clinical applications.},
subtyp = {Review Article},
keywords = {Humans / Hypoxia-Ischemia, Brain: therapy / Infant, Newborn
/ Hypothermia, Induced: methods / Neuroprotective Agents:
therapeutic use / Neuroprotection / Asphyxia Neonatorum:
therapy / Asphyxia Neonatorum: complications /
Hypoxic-ischemic encephalopathy (HIE) (Other) /
Neuroprotection (Other) / Newborn (Other) / Neuroprotective
Agents (NLM Chemicals)},
cin = {AG Sabir},
ddc = {610},
cid = {I:(DE-2719)5000032},
pnm = {352 - Disease Mechanisms (POF4-352)},
pid = {G:(DE-HGF)POF4-352},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:40887401},
doi = {10.1016/j.semperi.2025.152128},
url = {https://pub.dzne.de/record/282628},
}