Home > Publications Database > Neuroprotective therapies for neonatal hypoxic-ischemic brain injury - a contemporary update. > print

001     282628
005     20251218103445.0
024 7 _ |a 10.1016/j.semperi.2025.152128
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024 7 _ |a 0146-0005
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024 7 _ |a 1558-075X
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037 _ _ |a DZNE-2025-01364
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Sabir, Hemmen
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245 _ _ |a Neuroprotective therapies for neonatal hypoxic-ischemic brain injury - a contemporary update.
260 _ _ |a Philadelphia, Pa.
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336 7 _ |a article
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520 _ _ |a Neonatal encephalopathy of hypoxic-ischemic origin remains a leading cause of global neonatal mortality. Over the past decades, various neuroprotective strategies have been explored; however, therapeutic hypothermia remains the only clinically approved intervention to date. This review outlines emerging and adjunctive treatment modalities beyond therapeutic hypothermia and emphasizes the critical need for robust and reproducible translational research to bridge the gap between preclinical findings and clinical applications.
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650 _ 7 |a Hypoxic-ischemic encephalopathy (HIE)
|2 Other
650 _ 7 |a Neuroprotection
|2 Other
650 _ 7 |a Newborn
|2 Other
650 _ 7 |a Neuroprotective Agents
|2 NLM Chemicals
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Hypoxia-Ischemia, Brain: therapy
|2 MeSH
650 _ 2 |a Infant, Newborn
|2 MeSH
650 _ 2 |a Hypothermia, Induced: methods
|2 MeSH
650 _ 2 |a Neuroprotective Agents: therapeutic use
|2 MeSH
650 _ 2 |a Neuroprotection
|2 MeSH
650 _ 2 |a Asphyxia Neonatorum: therapy
|2 MeSH
650 _ 2 |a Asphyxia Neonatorum: complications
|2 MeSH
773 _ _ |a 10.1016/j.semperi.2025.152128
|g Vol. 49, no. 8, p. 152128 -
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|p 152128
|t Seminars in perinatology
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910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
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