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@INPROCEEDINGS{Buchholz:283039,
      author       = {Buchholz, Maresa and Michalowsky, Bernhard and Raedke,
                      Anika and Platen, Moritz and Scharf, Annelie and Kleinke,
                      Fabian and van den Berg, Neeltje and Hoffmann, Wolfgang},
      title        = {{E}fficacy and {E}ffectiveness of {E}xtended {N}ursing
                      {R}oles in {P}rimary {D}ementia {C}are ‐ {R}esults of the
                      {M}ulticenter, {C}luster‐randomized {T}rial},
      journal      = {Alzheimer's and dementia},
      volume       = {21},
      number       = {S4},
      issn         = {1552-5260},
      reportid     = {DZNE-2025-01446},
      pages        = {e104268},
      year         = {2025},
      abstract     = {Background: Extended nursing roles in dementia care can
                      improve treatment, care, and patient and caregiver outcomes.
                      We tested the efficacy and cost-effectiveness in People
                      living with Dementia (PlwD) and caregivers.Method: We
                      analyzed data from 417 PlwD within the multicenter,
                      cluster-randomized InDePendent trial six months after
                      baseline. Specifically qualified nurses carried out advanced
                      dementia care management tailored to patient's and
                      caregiver's needs. Outcomes includes unmet needs (CANE),
                      Quality of Life (QoL-AD, EQ-5D), Caregiver burden (Zarit),
                      and cost-effectiveness (FIMA, RUD).Result: PlwD receiving
                      the intervention had $74\%$ lower unmet needs (0.26,
                      $CI95\%0.17-0.40,$ p <0.001) and higher quality of life
                      (0.04, $CI95\%$ 0.01–0.07, p = 0.017) than controls. There
                      was a gain in QALY (0.01, $CI95\%-0.001-0.018)$ at slightly
                      higher costs (1,425€, $CI95\%$ 638-2,211). There was no
                      effect on caregiver burden.Conclusion:The results provide
                      evidence for the efficacy and effectiveness of extended
                      nursing roles in dementia care, demonstrating that extended
                      nursing roles reduce unmet needs and improve quality of
                      life.},
      month         = {Jul},
      date          = {2025-07-27},
      organization  = {Alzheimer’s Association
                       International Conference, Toronto
                       (Canada), 27 Jul 2025 - 31 Jul 2025},
      keywords     = {Humans / Dementia: nursing / Dementia: psychology /
                      Dementia: economics / Caregivers: psychology / Quality of
                      Life: psychology / Female / Male / Cost-Benefit Analysis /
                      Aged / Aged, 80 and over},
      cin          = {AG Hoffmann / AG Michalowsky},
      ddc          = {610},
      cid          = {I:(DE-2719)1510600 / I:(DE-2719)5000067},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)1 / PUB:(DE-HGF)16},
      doi          = {10.1002/alz70858_104268},
      url          = {https://pub.dzne.de/record/283039},
}