%0 Conference Paper
%A Boscheck, Hanna
%A Liebscher, Maxie
%A Delia, Ylenia
%A Mauer, René
%A Peters, Oliver
%A Priller, Josef
%A Schneider, Anja
%A Wiltfang, Jens
%A Buerger, Katharina
%A Perneczky, Robert
%A Teipel, Stefan
%A Laske, Christoph
%A Spottke, Annika
%A Brosseron, Frederic
%A Yakupov, Renat
%A Ziegler, Gabriel
%A Kleineidam, Luca
%A Jessen, Frank
%A Düzel, Emrah
%A Wagner, Michael
%A Roeske, Sandra
%A Marchant, Natalie L
%A Gloeckner, Franka
%A Klimecki-Lenz, Olga Maria
%A Wirth, Miranka
%T Associations of cognitive debt and cognitive reserve with mixed brain pathology and cognition
%J Alzheimer's and dementia
%V 21
%N Suppl 2
%@ 1552-5260
%M DZNE-2025-01460
%P e102595
%D 2025
%X Behavioral risk or protective factors related to 'cognitive debt' and 'cognitive reserve' may influence brain pathology and cognition and thereby contribute to resilience in aging. This cross-sectional study examined direct and indirect associations of cognitive debt (risk factor) and cognitive reserve (protective factor) with mixed brain pathologies and cognition in older adults.A sample of N = 298 non-demented older adults (mean age=70 years, 56
%B Alzheimer’s Association International Conference
%C 27 Jul 2025 - 31 Jul 2025, Toronto (Canada)
Y2 27 Jul 2025 - 31 Jul 2025
M2 Toronto, Canada
%K Humans
%K Male
%K Aged
%K Female
%K Cross-Sectional Studies
%K Biomarkers
%K Cognitive Reserve: physiology
%K Brain: pathology
%K Amyloid beta-Peptides: metabolism
%K Neuropsychological Tests
%K Magnetic Resonance Imaging
%K Alzheimer Disease
%K White Matter: pathology
%K Hippocampus: pathology
%K Aged, 80 and over
%K Biomarkers (NLM Chemicals)
%K Amyloid beta-Peptides (NLM Chemicals)
%F PUB:(DE-HGF)1 ; PUB:(DE-HGF)16
%9 AbstractJournal Article
%$ pmid:41450093
%2 pmc:PMC12741494
%R 10.1002/alz70856_102595
%U https://pub.dzne.de/record/283053