TY  - JOUR
AU  - Stiehm, M.
AU  - Nilsson, C.
AU  - Skogar, Ö
AU  - Walter, U.
TI  - The diagnostic value of transcranial sonography in Swedish parkinsonism patients: A retrospective cohort study with long-term follow-up.
JO  - Clinical parkinsonism & related disorders
VL  - 13
SN  - 2590-1125
CY  - Amsterdam
PB  - Elsevier
M1  - DZNE-2026-00015
SP  - 100411
PY  - 2025
AB  - Although transcranial sonography (TCS) assessing hyperechogenic substantia nigra (SN+) as biomarker for Parkinsońs disease (PD) has been introduced elsewhere, the clinical relevance and accuracy in a Swedish population is still unknown.This retrospective single-center study included 74 patients with predominantly early-stage parkinsonism at first visit who had been examined by TCS from 2013 to 2017 to determine the SN+ biomarker status in relation to PD, atypical parkinsonian disorders (APS), essential tremor (ET) and vascular/secondary/ unspecified parkinsonism, with the aim of long-term follow-up to confirm the clinical diagnosis. The cut-off value for SN+ was regarded as the 90 
KW  - Essential tremor (Other)
KW  - Hyperechogenicity (Other)
KW  - Movement disorders (Other)
KW  - Parkinsonism (Other)
KW  - Parkinsońs disease (Other)
KW  - Substantia nigra (Other)
KW  - Transcranial sonography (Other)
KW  - Ultrasound (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:41479687
C2  - pmc:PMC12754217
DO  - DOI:10.1016/j.prdoa.2025.100411
UR  - https://pub.dzne.de/record/283119
ER  -