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@ARTICLE{Gulban:283181,
      author       = {Gulban, Omer Faruk and Stirnberg, Rüdiger and Tse, Desmond
                      Ho Yan and Pizzuti, Alessandra and Koiso, Kenshu and
                      Archila-Melendez, Mario Eduardo and Huber, Laurentius Renzo
                      and Bollmann, Saskia and Goebel, Rainer and Kay, Kendrick
                      and Ivanov, Dimo},
      title        = {{W}hole-brain meso-vein imaging in living humans using fast
                      7-{T} {MRI}.},
      journal      = {Science advances},
      volume       = {12},
      number       = {2},
      issn         = {2375-2548},
      address      = {Washington, DC [u.a.]},
      publisher    = {Assoc.},
      reportid     = {DZNE-2026-00060},
      pages        = {eaea4540},
      year         = {2026},
      abstract     = {Noninvasive measurement of the human brain's
                      angioarchitecture is essential for understanding functional
                      neuroimaging signals, diagnosing cerebrovascular diseases,
                      and tracking neurodegeneration. Ultrahigh-field MRI now
                      enables mesoscopic (<0.5 millimeters) imaging, revealing
                      vascular details previously inaccessible in vivo. Yet
                      current approaches face two barriers: Scan times often
                      exceed 40 minutes, and the conventional visualization
                      methods remain limited for navigating the vasculature. Here,
                      we present a fast whole-brain MRI protocol that resolves the
                      venous network at 0.35 millimeters in under 7 minutes. We
                      also introduce processing and visualization techniques that
                      distinguish vessel types and more intuitively navigate the
                      vasculature. These advances allow in vivo reproduction of
                      the seminal vasculature images of Henri M. Duvernoy and
                      provide whole-brain intracortical meso-vein maps in humans.
                      Our methods lay the groundwork for detailed examination of
                      vascular organization across individuals, brain regions, and
                      cortical layers. More generally, these methods make
                      mesoscopic imaging of angioarchitecture viable for broad
                      neuroscientific and clinical applications.},
      keywords     = {Humans / Brain: blood supply / Brain: diagnostic imaging /
                      Magnetic Resonance Imaging: methods / Male / Female / Adult
                      / Neuroimaging: methods / Image Processing,
                      Computer-Assisted / Cerebral Veins: diagnostic imaging},
      cin          = {AG Stöcker},
      ddc          = {500},
      cid          = {I:(DE-2719)1013026},
      pnm          = {354 - Disease Prevention and Healthy Aging (POF4-354)},
      pid          = {G:(DE-HGF)POF4-354},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:41512066},
      pmc          = {pmc:PMC12787541},
      doi          = {10.1126/sciadv.aea4540},
      url          = {https://pub.dzne.de/record/283181},
}