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001     284070
005     20260122094105.0
024 7 _ |2 originalID
|a corda_____he::101247604
024 7 _ |2 CORDIS
|a G:(EU-Grant)101247604
|d 101247604
024 7 _ |2 CORDIS
|a G:(EU-Call)ERC-2025-POC
|d ERC-2025-POC
024 7 _ |2 doi
|a 10.3030/101247604
035 _ _ |a G:(EU-Grant)101247604
150 _ _ |a OPENing biological barriers using Shell-Engineered Shape-Adaptable Microbubble Enhancers
|y 2025-10-01 - 2027-03-31
372 _ _ |a ERC-2025-POC
|s 2025-10-01
|t 2027-03-31
450 _ _ |a Open-SESAME
|w d
|y 2025-10-01 - 2027-03-31
510 1 _ |0 I:(DE-588b)5098525-5
|a European Union
|b CORDIS
680 _ _ |a Microbubles unlocking next-gen drug delivery. Delivering drugs effectively across biological barriers, such as the blood-brain barrier or dense tumour tissue, remains a challenge. Therapies may fail because they cannot reach their intended targets in sufficient doses without causing harmful side effects. Ultrasound-responsive microbubbles can work to temporarily open pathways for drugs to penetrate otherwise resistant tissues. The ERC-funded Open-SESAME project is developing a modular microbubble platform. Researchers will refine scalable synthesis methods, test performance in brain and tumour models, and strengthen intellectual property for future commercialisation. By combining preclinical validation with market analysis, Open-SESAME aims to deliver an investor-ready plan that could transform treatment for patients with high unmet medical needs.
909 C O |o oai:publications.rwth-aachen.de:1025237
|p authority:GRANT
|p authority
909 C O |o oai:publications.rwth-aachen.de:1025237
980 _ _ |a G
980 _ _ |a AUTHORITY
980 _ _ |a CORDIS

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