guest ::
| Home > In process > Myocardial injury in patients with acute ischemic stroke: Prevalence and types of triggers of myocardial demand ischemia. > print |
| Home > In process > Myocardial injury in patients with acute ischemic stroke: Prevalence and types of triggers of myocardial demand ischemia. > print |
| 001 | 285001 | ||
| 005 | 20260202111530.0 | ||
| 024 | 7 | _ | |a 10.1093/esj/23969873251346008 |2 doi |
| 024 | 7 | _ | |a pmid:41614487 |2 pmid |
| 024 | 7 | _ | |a 2396-9873 |2 ISSN |
| 024 | 7 | _ | |a 2396-9881 |2 ISSN |
| 037 | _ | _ | |a DZNE-2026-00135 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Stengl, Helena |0 P:(DE-2719)9003150 |b 0 |e First author |
| 245 | _ | _ | |a Myocardial injury in patients with acute ischemic stroke: Prevalence and types of triggers of myocardial demand ischemia. |
| 260 | _ | _ | |a London |c 2026 |b Sage Publishing |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1770027093_15529 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a Acute myocardial injury occurs in about every fourth patient in the early phase after ischemic stroke. It may be caused by an imbalance between myocardial oxygen supply and demand, potentially leading to type 2 myocardial infarction (MI). However, little is known about the prevalence of potential triggers of such demand ischemia in acute stroke.Consecutive patients with and without post-stroke acute myocardial injury (elevated high-sensitivity cardiac troponin T [hs-cTnT] levels with a rise/fall >20%) were matched for age and sex and retrospectively screened for presence of predefined triggering conditions of myocardial demand ischemia and fulfillment of diagnostic criteria for acute MI.Among 508 stroke patients analyzed (median age 81 [73-86] years, 52% female), predefined potential triggers of demand ischemia were present in 107/254 (42%) patients with acute myocardial injury and in 61/254 (24%) matched controls (adjusted OR 2.30, 95%CI 1.51-3.52, p < 0.001). Patients with a trigger were older, more often female, had more severe strokes, and more often insular cortex involvement. The most prevalent triggers were respiratory failure, sustained hypertension, supraventricular tachyarrhythmia, and hemodynamic shock. MI criteria were fulfilled in 44/254 (17%) patients with acute myocardial injury including 27/44 (61.4%) with a trigger of demand ischemia (i.e. suspected type 2 MI).Conditions triggering a myocardial oxygen demand/supply mismatch are highly prevalent in patients with acute myocardial injury detected after stroke, notably in those fulfilling the criteria of acute MI. Stroke-specific aspects such as stroke severity or lesion location may play a role in the development of such triggers. |
| 536 | _ | _ | |a 353 - Clinical and Health Care Research (POF4-353) |0 G:(DE-HGF)POF4-353 |c POF4-353 |f POF IV |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, , Journals: pub.dzne.de |
| 650 | _ | 7 | |a 4th UDMI |2 Other |
| 650 | _ | 7 | |a Ischemic stroke |2 Other |
| 650 | _ | 7 | |a Stroke-Heart Syndrome |2 Other |
| 650 | _ | 7 | |a acute myocardial injury |2 Other |
| 650 | _ | 7 | |a central autonomic network% |2 Other |
| 650 | _ | 7 | |a demand ischemia |2 Other |
| 650 | _ | 7 | |a high-sensitivity cardiac troponin T |2 Other |
| 650 | _ | 7 | |a type 2 MI |2 Other |
| 650 | _ | 7 | |a Troponin T |2 NLM Chemicals |
| 650 | _ | 2 | |a Humans |2 MeSH |
| 650 | _ | 2 | |a Female |2 MeSH |
| 650 | _ | 2 | |a Male |2 MeSH |
| 650 | _ | 2 | |a Aged |2 MeSH |
| 650 | _ | 2 | |a Ischemic Stroke: complications |2 MeSH |
| 650 | _ | 2 | |a Ischemic Stroke: epidemiology |2 MeSH |
| 650 | _ | 2 | |a Prevalence |2 MeSH |
| 650 | _ | 2 | |a Aged, 80 and over |2 MeSH |
| 650 | _ | 2 | |a Retrospective Studies |2 MeSH |
| 650 | _ | 2 | |a Myocardial Ischemia: epidemiology |2 MeSH |
| 650 | _ | 2 | |a Myocardial Ischemia: etiology |2 MeSH |
| 650 | _ | 2 | |a Troponin T: blood |2 MeSH |
| 650 | _ | 2 | |a Myocardial Infarction: epidemiology |2 MeSH |
| 650 | _ | 2 | |a Myocardial Infarction: etiology |2 MeSH |
| 650 | _ | 2 | |a Stroke: complications |2 MeSH |
| 650 | _ | 2 | |a Stroke: epidemiology |2 MeSH |
| 700 | 1 | _ | |a Böhme, Sophie |0 P:(DE-2719)9003672 |b 1 |u dzne |
| 700 | 1 | _ | |a Richter, Oskar |b 2 |
| 700 | 1 | _ | |a Hellwig, Simon |b 3 |
| 700 | 1 | _ | |a Klammer, Markus G |0 0000-0002-8990-262X |b 4 |
| 700 | 1 | _ | |a Ganeshan, Ramanan |b 5 |
| 700 | 1 | _ | |a Reimann, Laura |0 P:(DE-HGF)0 |b 6 |
| 700 | 1 | _ | |a Audebert, Heinrich J |0 0000-0002-4785-0366 |b 7 |
| 700 | 1 | _ | |a Doehner, Wolfram |0 0000-0001-7598-708X |b 8 |
| 700 | 1 | _ | |a Nolte, Christian H |0 P:(DE-2719)9000234 |b 9 |
| 700 | 1 | _ | |a Endres, Matthias |0 P:(DE-2719)2811033 |b 10 |
| 700 | 1 | _ | |a Scheitz, Jan F |0 P:(DE-2719)9001514 |b 11 |
| 773 | _ | _ | |a 10.1093/esj/23969873251346008 |g Vol. 11, no. 1, p. 23969873251346008 |0 PERI:(DE-600)2851287-X |n 1 |p 23969873251346008 |t European stroke journal |v 11 |y 2026 |x 2396-9873 |
| 856 | 4 | _ | |u https://pub.dzne.de/record/285001/files/DZNE-2026-00135_Restricted.pdf |
| 856 | 4 | _ | |u https://pub.dzne.de/record/285001/files/DZNE-2026-00135_Restricted.pdf?subformat=pdfa |x pdfa |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 0 |6 P:(DE-2719)9003150 |
| 910 | 1 | _ | |a External Institute |0 I:(DE-HGF)0 |k Extern |b 1 |6 P:(DE-2719)9003672 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 6 |6 P:(DE-HGF)0 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 10 |6 P:(DE-2719)2811033 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Neurodegenerative Diseases |1 G:(DE-HGF)POF4-350 |0 G:(DE-HGF)POF4-353 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-300 |4 G:(DE-HGF)POF |v Clinical and Health Care Research |x 0 |
| 915 | _ | _ | |a National-Konsortium |0 StatID:(DE-HGF)0430 |2 StatID |d 2025-11-07 |w ger |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |b EUR STROKE J : 2022 |d 2025-11-07 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |d 2025-11-07 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2025-11-07 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0320 |2 StatID |b PubMed Central |d 2025-11-07 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Clarivate Analytics Master Journal List |d 2025-11-07 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1110 |2 StatID |b Current Contents - Clinical Medicine |d 2025-11-07 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0160 |2 StatID |b Essential Science Indicators |d 2025-11-07 |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0113 |2 StatID |b Science Citation Index Expanded |d 2025-11-07 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |d 2025-11-07 |
| 915 | _ | _ | |a IF >= 5 |0 StatID:(DE-HGF)9905 |2 StatID |b EUR STROKE J : 2022 |d 2025-11-07 |
| 920 | 1 | _ | |0 I:(DE-2719)1811005 |k AG Endres |l Interdisciplinary Dementia Research |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a EDITORS |
| 980 | _ | _ | |a VDBINPRINT |
| 980 | _ | _ | |a I:(DE-2719)1811005 |
| 980 | _ | _ | |a UNRESTRICTED |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|