TY  - JOUR
AU  - Zhang, Lanyue
AU  - Antabi, Mohamad Ali
AU  - Mattar, Jana
AU  - El Bounkari, Omar
AU  - Fang, Rong
AU  - Waegemann, Karin
AU  - Bode, Felix J
AU  - Stösser, Sebastian
AU  - Hermann, Peter
AU  - Liman, Thomas G
AU  - Nolte, Christian
AU  - Ikenberg, Benno
AU  - Bernkopf, Kathleen
AU  - Petzold, Gabor C
AU  - Bernhagen, Jürgen
AU  - Dichgans, Martin
AU  - Georgakis, Marios K
TI  - Circulating cytokine levels and 5-year vascular recurrence after stroke: A multicenter prospective cohort study.
JO  - European stroke journal
VL  - 11
IS  - 1
SN  - 2396-9873
CY  - London
PB  - Sage Publishing
M1  - DZNE-2026-00139
SP  - 23969873251360145
PY  - 2026
AB  - Anti-inflammatory therapies are tested in randomized trials for secondary stroke prevention. Detecting inflammatory biomarkers that predict vascular recurrence could optimize patient selection for these trials.In a multicenter prospective cohort study, we measured plasma levels of 22 inflammatory cytokines in 486 acute stroke patients (474 ischemic strokes and 12 intracerebral hemorrhages; median age 68 years, 34
KW  - Humans
KW  - Female
KW  - Male
KW  - Aged
KW  - Prospective Studies
KW  - Recurrence
KW  - Middle Aged
KW  - Cytokines: blood
KW  - Ischemic Attack, Transient: blood
KW  - Biomarkers: blood
KW  - Stroke: blood
KW  - Follow-Up Studies
KW  - Risk Factors
KW  - Ischemic Stroke: blood
KW  - Cohort Studies
KW  - Stroke (Other)
KW  - cytokines (Other)
KW  - inflammation (Other)
KW  - recurrence (Other)
KW  - risk prediction (Other)
KW  - Cytokines (NLM Chemicals)
KW  - Biomarkers (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:41614521
DO  - DOI:10.1093/esj/23969873251360145
UR  - https://pub.dzne.de/record/285005
ER  -