| 001 | 285026 | ||
| 005 | 20260205153658.0 | ||
| 020 | _ | _ | |a 978-1-0716-5153-7 (print) |
| 020 | _ | _ | |a 978-1-0716-5154-4 (electronic) |
| 024 | 7 | _ | |a 10.1007/978-1-0716-5154-4_12 |2 doi |
| 024 | 7 | _ | |a pmid:41629717 |2 pmid |
| 024 | 7 | _ | |a 1064-3745 |2 ISSN |
| 024 | 7 | _ | |a 1940-6029 |2 ISSN |
| 037 | _ | _ | |a DZNE-2026-00151 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 570 |
| 100 | 1 | _ | |a Hartmann, Celia L |0 P:(DE-2719)9002121 |b 0 |e First author |u dzne |
| 245 | _ | _ | |a Laser-Capture Microdissection Followed by ATAC-Seq. |
| 260 | _ | _ | |a New York, NY |c 2026 |b Springer US |
| 295 | 1 | 0 | |a Laser Capture Microdissection / Noberini, Roberta (Editor) ; New York, NY : Springer US, 2026, Chapter 12 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-0716-5153-7=978-1-0716-5154-4 ; doi:10.1007/978-1-0716-5154-4 |
| 300 | _ | _ | |a 151 - 162 |
| 336 | 7 | _ | |a BOOK_CHAPTER |2 ORCID |
| 336 | 7 | _ | |a Book Section |0 7 |2 EndNote |
| 336 | 7 | _ | |a bookPart |2 DRIVER |
| 336 | 7 | _ | |a INBOOK |2 BibTeX |
| 336 | 7 | _ | |a Output Types/Book chapter |2 DataCite |
| 336 | 7 | _ | |a Contribution to a book |b contb |m contb |0 PUB:(DE-HGF)7 |s 1770302013_11292 |2 PUB:(DE-HGF) |
| 490 | 0 | _ | |a Methods in Molecular Biology |v 3015 |
| 520 | _ | _ | |a Laser-capture microdissection (LCM) enables the collection of regions of interest from target tissues, making it compatible with a number of spatially resolved downstream omics applications. Here, we provide a detailed protocol for LCM coupled to ATAC-seq (LCM-ATAC-seq) for the spatial analysis of chromatin landscape based on the method published by Carraro et al. (Cell Rep Methods 3:100598, 2023). LCM-ATAC-seq allows the efficient capture down to single nuclei and can be combined with the morphological staining of target cell populations to characterize chromatin states in fresh-frozen tissue samples. |
| 536 | _ | _ | |a 354 - Disease Prevention and Healthy Aging (POF4-354) |0 G:(DE-HGF)POF4-354 |c POF4-354 |f POF IV |x 0 |
| 536 | _ | _ | |a 351 - Brain Function (POF4-351) |0 G:(DE-HGF)POF4-351 |c POF4-351 |f POF IV |x 1 |
| 536 | _ | _ | |a 352 - Disease Mechanisms (POF4-352) |0 G:(DE-HGF)POF4-352 |c POF4-352 |f POF IV |x 2 |
| 588 | _ | _ | |a Dataset connected to CrossRef Book Series, PubMed, , Journals: pub.dzne.de |
| 650 | _ | 7 | |a ATAC-seq |2 Other |
| 650 | _ | 7 | |a Chromatin accessibility |2 Other |
| 650 | _ | 7 | |a Laser-capture microdissection |2 Other |
| 650 | _ | 7 | |a Morphological staining |2 Other |
| 650 | _ | 7 | |a Spatial omics |2 Other |
| 650 | _ | 7 | |a Chromatin |2 NLM Chemicals |
| 650 | _ | 2 | |a Laser Capture Microdissection: methods |2 MeSH |
| 650 | _ | 2 | |a Chromatin: genetics |2 MeSH |
| 650 | _ | 2 | |a Chromatin Immunoprecipitation Sequencing: methods |2 MeSH |
| 650 | _ | 2 | |a Humans |2 MeSH |
| 650 | _ | 2 | |a High-Throughput Nucleotide Sequencing: methods |2 MeSH |
| 693 | _ | _ | |0 EXP:(DE-2719)PRECISE-20190321 |5 EXP:(DE-2719)PRECISE-20190321 |e Platform for Single Cell Genomics and Epigenomics at DZNE University of Bonn |x 0 |
| 700 | 1 | _ | |a Schultze, Joachim L |0 P:(DE-2719)2811660 |b 1 |u dzne |
| 700 | 1 | _ | |a Beyer, Marc D |0 P:(DE-2719)2812219 |b 2 |u dzne |
| 700 | 1 | _ | |a Carraro, Caterina |0 P:(DE-2719)9001303 |b 3 |e Last author |u dzne |
| 773 | _ | _ | |a 10.1007/978-1-0716-5154-4_12 |
| 856 | 4 | _ | |u https://pub.dzne.de/record/285026/files/DZNE-2026-00151_Restricted.pdf |
| 856 | 4 | _ | |u https://pub.dzne.de/record/285026/files/DZNE-2026-00151_Restricted.pdf?subformat=pdfa |x pdfa |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 0 |6 P:(DE-2719)9002121 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 1 |6 P:(DE-2719)2811660 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 2 |6 P:(DE-2719)2812219 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 3 |6 P:(DE-2719)9001303 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Neurodegenerative Diseases |1 G:(DE-HGF)POF4-350 |0 G:(DE-HGF)POF4-354 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-300 |4 G:(DE-HGF)POF |v Disease Prevention and Healthy Aging |x 0 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Neurodegenerative Diseases |1 G:(DE-HGF)POF4-350 |0 G:(DE-HGF)POF4-351 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-300 |4 G:(DE-HGF)POF |v Brain Function |x 1 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Neurodegenerative Diseases |1 G:(DE-HGF)POF4-350 |0 G:(DE-HGF)POF4-352 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-300 |4 G:(DE-HGF)POF |v Disease Mechanisms |x 2 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |d 2025-11-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2025-11-05 |
| 920 | 1 | _ | |0 I:(DE-2719)1013038 |k AG Schultze |l Clinical Single Cell Omics (CSCO) / Systems Medicine |x 0 |
| 920 | 1 | _ | |0 I:(DE-2719)1013035 |k AG Beyer |l Immunogenomics and Neurodegeneration |x 1 |
| 920 | 1 | _ | |0 I:(DE-2719)1013031 |k PRECISE |l Platform for Single Cell Genomics and Epigenomics |x 2 |
| 980 | _ | _ | |a contb |
| 980 | _ | _ | |a EDITORS |
| 980 | _ | _ | |a VDBINPRINT |
| 980 | _ | _ | |a I:(DE-2719)1013038 |
| 980 | _ | _ | |a I:(DE-2719)1013035 |
| 980 | _ | _ | |a I:(DE-2719)1013031 |
| 980 | _ | _ | |a UNRESTRICTED |
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