001     285026
005     20260205153658.0
020 _ _ |a 978-1-0716-5153-7 (print)
020 _ _ |a 978-1-0716-5154-4 (electronic)
024 7 _ |a 10.1007/978-1-0716-5154-4_12
|2 doi
024 7 _ |a pmid:41629717
|2 pmid
024 7 _ |a 1064-3745
|2 ISSN
024 7 _ |a 1940-6029
|2 ISSN
037 _ _ |a DZNE-2026-00151
041 _ _ |a English
082 _ _ |a 570
100 1 _ |a Hartmann, Celia L
|0 P:(DE-2719)9002121
|b 0
|e First author
|u dzne
245 _ _ |a Laser-Capture Microdissection Followed by ATAC-Seq.
260 _ _ |a New York, NY
|c 2026
|b Springer US
295 1 0 |a Laser Capture Microdissection / Noberini, Roberta (Editor) ; New York, NY : Springer US, 2026, Chapter 12 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-0716-5153-7=978-1-0716-5154-4 ; doi:10.1007/978-1-0716-5154-4
300 _ _ |a 151 - 162
336 7 _ |a BOOK_CHAPTER
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336 7 _ |a Book Section
|0 7
|2 EndNote
336 7 _ |a bookPart
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336 7 _ |a INBOOK
|2 BibTeX
336 7 _ |a Output Types/Book chapter
|2 DataCite
336 7 _ |a Contribution to a book
|b contb
|m contb
|0 PUB:(DE-HGF)7
|s 1770302013_11292
|2 PUB:(DE-HGF)
490 0 _ |a Methods in Molecular Biology
|v 3015
520 _ _ |a Laser-capture microdissection (LCM) enables the collection of regions of interest from target tissues, making it compatible with a number of spatially resolved downstream omics applications. Here, we provide a detailed protocol for LCM coupled to ATAC-seq (LCM-ATAC-seq) for the spatial analysis of chromatin landscape based on the method published by Carraro et al. (Cell Rep Methods 3:100598, 2023). LCM-ATAC-seq allows the efficient capture down to single nuclei and can be combined with the morphological staining of target cell populations to characterize chromatin states in fresh-frozen tissue samples.
536 _ _ |a 354 - Disease Prevention and Healthy Aging (POF4-354)
|0 G:(DE-HGF)POF4-354
|c POF4-354
|f POF IV
|x 0
536 _ _ |a 351 - Brain Function (POF4-351)
|0 G:(DE-HGF)POF4-351
|c POF4-351
|f POF IV
|x 1
536 _ _ |a 352 - Disease Mechanisms (POF4-352)
|0 G:(DE-HGF)POF4-352
|c POF4-352
|f POF IV
|x 2
588 _ _ |a Dataset connected to CrossRef Book Series, PubMed, , Journals: pub.dzne.de
650 _ 7 |a ATAC-seq
|2 Other
650 _ 7 |a Chromatin accessibility
|2 Other
650 _ 7 |a Laser-capture microdissection
|2 Other
650 _ 7 |a Morphological staining
|2 Other
650 _ 7 |a Spatial omics
|2 Other
650 _ 7 |a Chromatin
|2 NLM Chemicals
650 _ 2 |a Laser Capture Microdissection: methods
|2 MeSH
650 _ 2 |a Chromatin: genetics
|2 MeSH
650 _ 2 |a Chromatin Immunoprecipitation Sequencing: methods
|2 MeSH
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a High-Throughput Nucleotide Sequencing: methods
|2 MeSH
693 _ _ |0 EXP:(DE-2719)PRECISE-20190321
|5 EXP:(DE-2719)PRECISE-20190321
|e Platform for Single Cell Genomics and Epigenomics at DZNE University of Bonn
|x 0
700 1 _ |a Schultze, Joachim L
|0 P:(DE-2719)2811660
|b 1
|u dzne
700 1 _ |a Beyer, Marc D
|0 P:(DE-2719)2812219
|b 2
|u dzne
700 1 _ |a Carraro, Caterina
|0 P:(DE-2719)9001303
|b 3
|e Last author
|u dzne
773 _ _ |a 10.1007/978-1-0716-5154-4_12
856 4 _ |u https://pub.dzne.de/record/285026/files/DZNE-2026-00151_Restricted.pdf
856 4 _ |u https://pub.dzne.de/record/285026/files/DZNE-2026-00151_Restricted.pdf?subformat=pdfa
|x pdfa
910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
|0 I:(DE-588)1065079516
|k DZNE
|b 0
|6 P:(DE-2719)9002121
910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
|0 I:(DE-588)1065079516
|k DZNE
|b 1
|6 P:(DE-2719)2811660
910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
|0 I:(DE-588)1065079516
|k DZNE
|b 2
|6 P:(DE-2719)2812219
910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
|0 I:(DE-588)1065079516
|k DZNE
|b 3
|6 P:(DE-2719)9001303
913 1 _ |a DE-HGF
|b Gesundheit
|l Neurodegenerative Diseases
|1 G:(DE-HGF)POF4-350
|0 G:(DE-HGF)POF4-354
|3 G:(DE-HGF)POF4
|2 G:(DE-HGF)POF4-300
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|v Disease Prevention and Healthy Aging
|x 0
913 1 _ |a DE-HGF
|b Gesundheit
|l Neurodegenerative Diseases
|1 G:(DE-HGF)POF4-350
|0 G:(DE-HGF)POF4-351
|3 G:(DE-HGF)POF4
|2 G:(DE-HGF)POF4-300
|4 G:(DE-HGF)POF
|v Brain Function
|x 1
913 1 _ |a DE-HGF
|b Gesundheit
|l Neurodegenerative Diseases
|1 G:(DE-HGF)POF4-350
|0 G:(DE-HGF)POF4-352
|3 G:(DE-HGF)POF4
|2 G:(DE-HGF)POF4-300
|4 G:(DE-HGF)POF
|v Disease Mechanisms
|x 2
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0200
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|b SCOPUS
|d 2025-11-05
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0300
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|b Medline
|d 2025-11-05
920 1 _ |0 I:(DE-2719)1013038
|k AG Schultze
|l Clinical Single Cell Omics (CSCO) / Systems Medicine
|x 0
920 1 _ |0 I:(DE-2719)1013035
|k AG Beyer
|l Immunogenomics and Neurodegeneration
|x 1
920 1 _ |0 I:(DE-2719)1013031
|k PRECISE
|l Platform for Single Cell Genomics and Epigenomics
|x 2
980 _ _ |a contb
980 _ _ |a EDITORS
980 _ _ |a VDBINPRINT
980 _ _ |a I:(DE-2719)1013038
980 _ _ |a I:(DE-2719)1013035
980 _ _ |a I:(DE-2719)1013031
980 _ _ |a UNRESTRICTED


LibraryCollectionCLSMajorCLSMinorLanguageAuthor
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