%0 Journal Article
%A Lischewski, Stella Andrea
%A Dogan, Imis
%A Giunti, Paola
%A Parkinson, Michael H
%A Mariotti, Caterina
%A Durr, Alexandra
%A Ewenczyk, Claire
%A Boesch, Sylvia
%A Nachbauer, Wolfgang
%A Klopstock, Thomas
%A Stendel, Claudia
%A de Rivera Garrido, Francisco Javier Rodríguez
%A Schöls, Ludger
%A Fleszar, Zofia
%A Klockgether, Thomas
%A Grobe-Einsler, Marcus
%A Giordano, Ilaria
%A Rai, Myriam
%A Pandolfo, Massimo
%A Jacobi, Heike
%A Hilgers, Ralf-Dieter
%A Schulz, Jörg B
%A Reetz, Kathrin
%T Analysis of a Modified Version of the Inventory of Non-Ataxia Signs Over 12 Years in Patients with Friedreich's Ataxia in the EFACTS Study.
%J Movement disorders
%V 41
%N 1
%@ 0885-3185
%C New York, NY
%I Wiley
%M DZNE-2026-00168
%P 200 - 211
%D 2026
%X Friedreich's ataxia is a rare, neurodegenerative, multisystem disorder. While ataxia is a hallmark, non-ataxia signs, including muscle weakness, spasticity, and dysphagia are equally disabling. The Inventory of Non-Ataxia Signs (INAS) is a symptom list transformable to a 16-item count.To evaluate the responsiveness of a modified INAS in this population.Participants were drawn from the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS). The modified INAS count (presence/absence, 0-16 scale) and modified INAS sum (severity-weighted, 0-84 scale) were evaluated using linear mixed-models and standardized response means (SRMs). Items rare (<5
%K Humans
%K Friedreich Ataxia: diagnosis
%K Friedreich Ataxia: physiopathology
%K Friedreich Ataxia: complications
%K Male
%K Female
%K Adult
%K Middle Aged
%K Young Adult
%K Severity of Illness Index
%K Adolescent
%K Child
%K Friedreich's ataxia (Other)
%K longitudinal (Other)
%K non‐ataxia symptoms (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:41070559
%2 pmc:PMC12882042
%R 10.1002/mds.70084
%U https://pub.dzne.de/record/285044