TY - JOUR
AU - Preßler, Hannah
AU - Schwarz, Lisa
AU - Streit, Simon
AU - Aigner, Annette
AU - Schleicher, Alicia
AU - Stascheit, Frauke
AU - Arlt, Friederike A
AU - Zinnow, Viktoria
AU - Khorassani, Tatjana
AU - Prüss, Harald
AU - Böhmerle, Wolfgang
AU - Meisel, Andreas
AU - Stenzel, Werner
AU - Scheibe, Franziska
TI - Clinical course and prognosis of chronic autoimmune neuropathies requiring intensive care: a retrospective cohort study.
JO - Journal of neurology
VL - 273
IS - 2
SN - 0367-004X
CY - [Darmstadt]
PB - Steinkopff
M1 - DZNE-2026-00243
SP - 165
PY - 2026
AB - Data on chronic autoimmune neuropathies (CAN) requiring intensive care unit (ICU) treatment are limited. This study investigated clinical and neuropathological features, immunotherapies, and outcomes of ICU-treated CAN patients.Retrospectively, we analyzed patients with CAN admitted to the ICU between 2007 and 2024. Outcomes, assessed by Inflammatory Neuropathy Cause and Treatment (INCAT) score and modified Rankin scale (mRS), were compared to age, sex, and diagnosis-matched non-ICU outpatients using ordinal and binary logistic regression.Among 21 included patients (chronic inflammatory demyelinating neuropathies (CIDP): n = 15, other CAN: n = 6), 95
KW - Humans
KW - Male
KW - Female
KW - Retrospective Studies
KW - Middle Aged
KW - Aged
KW - Prognosis
KW - Critical Care
KW - Adult
KW - Polyradiculoneuropathy, Chronic Inflammatory Demyelinating: therapy
KW - Polyradiculoneuropathy, Chronic Inflammatory Demyelinating: diagnosis
KW - Polyradiculoneuropathy, Chronic Inflammatory Demyelinating: pathology
KW - Immunotherapy
KW - Intensive Care Units
KW - Autoimmune Diseases of the Nervous System: therapy
KW - Autoimmune Diseases of the Nervous System: diagnosis
KW - Autologous stem cell transplantation (Other)
KW - Chronic autoimmune neuropathies (Other)
KW - Daratumumab (Other)
KW - Intensive care unit (Other)
LB - PUB:(DE-HGF)16
C6 - pmid:41739210
C2 - pmc:PMC12935830
DO - DOI:10.1007/s00415-026-13694-4
UR - https://pub.dzne.de/record/285465
ER -