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@ARTICLE{Serger:285473,
author = {Serger, Matthias and Stirnberg, Rüdiger and Ehses, Philipp
and Riedel, Malte and Ulrich, Thomas and Le Ster, Caroline
and Mauconduit, Franck and Gras, Vincent and Amadon, Alexis
and Vignaud, Alexandre and Chu, Son and Gunamony, Shajan and
Zaitsev, Maxim and Boulant, Nicolas and Pruessmann, Klaas P
and Stoecker, Tony},
title = {{M}otion- and {F}ield-{R}obust {M}esoscopic {W}hole-{B}rain
{T} 2 * $$ {{T}}_2^{\ast } $$ -{W}eighted {I}maging at 7 and
11.7 {T} {U}sing {S}ervo {N}avigation.},
journal = {Magnetic resonance in medicine},
volume = {95},
number = {5},
issn = {1522-2594},
address = {New York, NY [u.a.]},
publisher = {Wiley-Liss},
reportid = {DZNE-2026-00250},
pages = {2658 - 2670},
year = {2026},
abstract = {To mitigate artifacts related to motion and field changes
in high-resolution T 2 * $$ {T}_2^{\ast } $$ -weighted human
brain imaging using servo navigation at ultra-high fields up
to 11.7 T.MR-based servo navigators were integrated into a
segmented 3D-EPI sequence to allow for prospective
correction of involuntary head motion and first-order shim
changes. Seven subjects were scanned with whole-brain
protocols at 0.3 mm isotropic resolution with and without
correction at 7 and 11.7 T. Validation was performed on
detailed brain vasculature in scans with involuntary
motion.Blurring of small veins was reduced by servo
navigation for all subjects and across field strengths. In
case of involuntary large motion, the method preserved image
quality, while uncorrected motion led to severe artifacts.
In case of microscopic motion, reduced blurring and shading
in the frontal lobe demonstrate the additional benefit of
prospective field drift correction.Servo-navigated segmented
3D-EPI improves 0.3 mm isotropic whole-brain T 2 * $$
{T}_2^{\ast } $$ -weighted imaging under realistic motion
and field changes within 5.5 to 11 min scan time at 11.7 and
7 T.},
keywords = {Humans / Brain: diagnostic imaging / Artifacts / Imaging,
Three-Dimensional: methods / Motion / Male / Adult / Female
/ Echo-Planar Imaging: methods / Algorithms / Image
Processing, Computer-Assisted: methods / Magnetic Resonance
Imaging: methods / Reproducibility of Results / 11.7 T
(Other) / 3D‐EPI (Other) / brain vasculature (Other) /
mesoscopic imaging (Other) / prospective motion correction
(Other) / servo navigation (Other)},
cin = {AG Stöcker},
ddc = {610},
cid = {I:(DE-2719)1013026},
pnm = {354 - Disease Prevention and Healthy Aging (POF4-354)},
pid = {G:(DE-HGF)POF4-354},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:41527210},
pmc = {pmc:PMC12962216},
doi = {10.1002/mrm.70251},
url = {https://pub.dzne.de/record/285473},
}