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@ARTICLE{Zhunussova:285738,
      author       = {Zhunussova, Alina and Loane, Clare and Kurt, Elif and
                      Femminella, Grazia Daniela and Lenzoni, Sabrina and Duckett,
                      Millie and Callaghan, Martina F and Weiskopf, Nikolaus and
                      Dolan, Raymond J and Howard, Robert and Düzel, Emrah and
                      Hämmerer, Dorothea},
      title        = {{P}upil dilation as a marker of attention/effort in aging
                      and mild cognitive impairment.},
      journal      = {Alzheimer's and dementia},
      volume       = {22},
      number       = {3},
      issn         = {1552-5260},
      address      = {Hoboken, NJ},
      publisher    = {Wiley},
      reportid     = {DZNE-2026-00295},
      pages        = {e71180},
      year         = {2026},
      abstract     = {Pupil dilation (PD) can be easily measured and reflects
                      responses to subjectively salient or cognitively demanding
                      events. It therefore holds promise as a cognitive marker,
                      especially for individuals with mild cognitive impairment
                      (MCI) or other neurodegenerative conditions with restricted
                      abilities to respond in cognitive assessments.We assessed PD
                      during two tasks, an oddball task for investigating
                      attentional allocation and a Simon task, which additionally
                      allows for investigating cognitive effort in younger adults
                      (YAs), older adults (OAs), and patients with MCI.PD is a
                      useful marker for investigating attention and cognitive
                      effort in MCI, as suggested by elevated PD to salient
                      stimuli in particular of individuals with better attentional
                      control in MCI patients, as well as YAs and OAs.Measurement
                      of PD may serve as an easy-to-administer measure to assess
                      changes in cognitive function in healthy aging and MCI.},
      keywords     = {Humans / Cognitive Dysfunction: physiopathology / Cognitive
                      Dysfunction: diagnosis / Male / Female / Aged / Pupil:
                      physiology / Attention: physiology / Aging: physiology /
                      Middle Aged / Neuropsychological Tests / Adult / Young Adult
                      / Aged, 80 and over / attentional modulation (Other) /
                      cognitive effort (Other) / locus coeruleus (Other) / mild
                      cognitive impairment (Other) / pupil dilation (Other)},
      cin          = {AG Düzel},
      ddc          = {610},
      cid          = {I:(DE-2719)5000006},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:41830112},
      doi          = {10.1002/alz.71180},
      url          = {https://pub.dzne.de/record/285738},
}