TY  - JOUR
AU  - Off, Johannes
AU  - Scherer, Maximilian
AU  - Peschke, Sophia
AU  - Kirschner, Angelina
AU  - Zhang, Weidong
AU  - Shaik, Juhi
AU  - Dong, Jing
AU  - Mehrkens, Jan-Hinnerk
AU  - Kaufmann, Elisabeth
AU  - Koeglsperger, Thomas
TI  - Psychometric reliability of patient-reported visual analogue scales in subthalamic nucleus deep brain stimulation programming for Parkinson's disease.
JO  - Brain communications
VL  - 8
IS  - 2
SN  - 2632-1297
CY  - [Oxford]
PB  - Oxford University Press
M1  - DZNE-2026-00353
SP  - fcag100
PY  - 2026
AB  - Subthalamic nucleus deep brain stimulation is an established therapy for Parkinson's disease, yet its programming relies heavily on subjective patient feedback. Visual analogue scales have been proposed to structure patient-reported outcome measures during programming, but their psychometric reliability has not been systematically evaluated. In this study, fifteen patients with bilateral subthalamic nucleus deep brain stimulation completed four structured experiments to assess the reliability of visual analogue scales: test-retest consistency, the effect of stimulation duration (15, 60, 120 s), the impact of unilateral deep brain stimulation withdrawal intervals (0, 10, 30 min), and contralateral stimulation ON versus OFF. Across all experiments, patients provided over 3000 visual analogue scale ratings, which were analyzed using correlation, regression, and Bland-Altman methods, with subgroup analyses examining motor phenotype, cognition, and disease burden. Visual analogue scale ratings demonstrated strong test-retest reliability (r = 0.70, R 2 = 0.53), with 83
KW  - Parkinson’s disease (PD) (Other)
KW  - deep brain stimulation (DBS) (Other)
KW  - visual analogue scale (VAS) (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:41924696
C2  - pmc:PMC13037577
DO  - DOI:10.1093/braincomms/fcag100
UR  - https://pub.dzne.de/record/285817
ER  -