TY  - JOUR
AU  - Blömer, Simon
AU  - Stöcker, Tony
AU  - Stirnberg, Rüdiger
TI  - Echo-Planar-Based Time-of-Flight Imaging Using a Modified Interleaved Flyback Trajectory.
JO  - Magnetic resonance in medicine
VL  - 95
IS  - 6
SN  - 1522-2594
CY  - New York, NY [u.a.]
PB  - Wiley-Liss
M1  - DZNE-2026-00359
SP  - 3131 - 3144
PY  - 2026
AB  - A modified interleaved flyback (miFB) approach is introduced, designed to mitigate flow artifacts caused by alternating readout polarities in Echo Planar Imaging (EPI), while preserving acquisition efficiency.We propose reconstructing odd and even echoes of 3D-EPI separately. To this end, the respective missing lines are acquired in interleaved shots with inverted polarity and an additional gradient pre-lobe. Thereby, high scan efficiency is maintained compared to unsampled flyback gradients. Our miFB approach is additionally combined with gradient moment smoothing and compared to the interleaved dual-echo with acceleration (IDEA) method in phantom and in vivo scans at 7 Tesla.Our results demonstrate a significant reduction in ghosting and signal dropout using the miFB approach, yielding comparable image quality to non-EPI acquisitions while reducing acquisition time by approximately half.The miFB approach offers a substantial reduction in flow artifacts, allowing for decreased acquisition times in TOF-MRA.
KW  - Echo-Planar Imaging: methods
KW  - Phantoms, Imaging
KW  - Artifacts
KW  - Algorithms
KW  - Humans
KW  - Imaging, Three-Dimensional: methods
KW  - Image Processing, Computer-Assisted: methods
KW  - 3D‐EPI (Other)
KW  - 7T (Other)
KW  - echo planar imaging (Other)
KW  - flow artifacts (Other)
KW  - magnetic resonance angiography (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:41588638
DO  - DOI:10.1002/mrm.70272
UR  - https://pub.dzne.de/record/285913
ER  -