000285915 001__ 285915
000285915 005__ 20260407160218.0
000285915 0247_ $$2doi$$a10.1016/j.neurot.2026.e00864
000285915 0247_ $$2pmid$$apmid:41764014
000285915 0247_ $$2pmc$$apmc:PMC12993401
000285915 0247_ $$2ISSN$$a1933-7213
000285915 0247_ $$2ISSN$$a1545-5343
000285915 0247_ $$2ISSN$$a1545-5351
000285915 0247_ $$2ISSN$$a1878-7479
000285915 037__ $$aDZNE-2026-00361
000285915 041__ $$aEnglish
000285915 082__ $$a610
000285915 1001_ $$aLiu, Jinlong$$b0
000285915 245__ $$aFunctional network reorganization following VIM-MRgFUS for essential tremor.
000285915 260__ $$a[Amsterdam]$$bElsevier B.V.$$c2026
000285915 3367_ $$2DRIVER$$aarticle
000285915 3367_ $$2DataCite$$aOutput Types/Journal article
000285915 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1775570369_6691
000285915 3367_ $$2BibTeX$$aARTICLE
000285915 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000285915 3367_ $$00$$2EndNote$$aJournal Article
000285915 520__ $$aMagnetic resonance-guided focused ultrasound (MRgFUS) is a promising, noninvasive therapeutic approach for essential tremor (ET), yet the effects of the respective lesions on functional brain network organization remain poorly understood. Here, we performed graph theory analysis to investigate changes in small-world properties and modular architecture in ET patients six months after unilateral MRgFUS of the thalamic ventral intermediate (VIM) nucleus. Small-worldness and normalized clustering coefficient increased significantly after MRgFUS, while clustering coefficient, characteristic path length, normalized characteristic path length, global efficiency, and local efficiency remained unchanged. Modular organization was largely preserved, but trend-level enhancements in inter-modular connectivity were observed between frontoparietal and subcortical modules, as well as between frontoparietal and frontotemporal-parietal modules. Within these modules, betweenness centrality increased significantly in specific cortical hubs, including the left superior frontal gyrus, right superior parietal lobule, and left postcentral gyrus. These findings indicate that unilateral VIM-MRgFUS induces selective functional network reorganization, particularly affecting relative clustering and nodal centrality patterns.
000285915 536__ $$0G:(DE-HGF)POF4-353$$a353 - Clinical and Health Care Research (POF4-353)$$cPOF4-353$$fPOF IV$$x0
000285915 588__ $$aDataset connected to CrossRef, PubMed, , Journals: pub.dzne.de
000285915 650_7 $$2Other$$aBrain networks
000285915 650_7 $$2Other$$aEssential tremor
000285915 650_7 $$2Other$$aGraph theory analysis
000285915 650_7 $$2Other$$aMRgFUS
000285915 650_7 $$2Other$$aVentral intermediate nucleus
000285915 650_2 $$2MeSH$$aHumans
000285915 650_2 $$2MeSH$$aEssential Tremor: diagnostic imaging
000285915 650_2 $$2MeSH$$aEssential Tremor: therapy
000285915 650_2 $$2MeSH$$aEssential Tremor: physiopathology
000285915 650_2 $$2MeSH$$aEssential Tremor: surgery
000285915 650_2 $$2MeSH$$aMale
000285915 650_2 $$2MeSH$$aFemale
000285915 650_2 $$2MeSH$$aMagnetic Resonance Imaging: methods
000285915 650_2 $$2MeSH$$aMiddle Aged
000285915 650_2 $$2MeSH$$aAged
000285915 650_2 $$2MeSH$$aVentral Thalamic Nuclei: diagnostic imaging
000285915 650_2 $$2MeSH$$aVentral Thalamic Nuclei: surgery
000285915 650_2 $$2MeSH$$aNerve Net: diagnostic imaging
000285915 7001_ $$0P:(DE-HGF)0$$aKrauss, Jonas$$b1
000285915 7001_ $$0P:(DE-2719)9000867$$aPurrer, Veronika$$b2$$udzne
000285915 7001_ $$aBorger, Valeri$$b3
000285915 7001_ $$aEssler, Markus$$b4
000285915 7001_ $$0P:(DE-2719)9001861$$aRadbruch, Alexander$$b5$$udzne
000285915 7001_ $$0P:(DE-2719)2000056$$aWüllner, Ullrich$$b6$$udzne
000285915 7001_ $$0P:(DE-2719)2812558$$aUpadhyay, Neeraj$$b7$$udzne
000285915 7001_ $$0P:(DE-2719)2810726$$aBoecker, Henning$$b8$$eLast author$$udzne
000285915 773__ $$0PERI:(DE-600)2279496-7$$a10.1016/j.neurot.2026.e00864$$gVol. 23, no. 2, p. e00864 -$$n2$$pe00864$$tNeurotherapeutics$$v23$$x1933-7213$$y2026
000285915 8564_ $$uhttps://pub.dzne.de/record/285915/files/DZNE-2026-00361.pdf$$yRestricted
000285915 8564_ $$uhttps://pub.dzne.de/record/285915/files/DZNE-2026-00361.pdf?subformat=pdfa$$xpdfa$$yRestricted
000285915 9101_ $$0I:(DE-588)1065079516$$6P:(DE-HGF)0$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b1$$kDZNE
000285915 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)9000867$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b2$$kDZNE
000285915 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)9001861$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b5$$kDZNE
000285915 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2000056$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b6$$kDZNE
000285915 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2812558$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b7$$kDZNE
000285915 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2810726$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b8$$kDZNE
000285915 9131_ $$0G:(DE-HGF)POF4-353$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vClinical and Health Care Research$$x0
000285915 915__ $$0StatID:(DE-HGF)3002$$2StatID$$aDEAL Springer$$d2025-11-06$$wger
000285915 915__ $$0StatID:(DE-HGF)3002$$2StatID$$aDEAL Springer$$d2025-11-06$$wger
000285915 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2025-11-06
000285915 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2025-11-06
000285915 915__ $$0StatID:(DE-HGF)0320$$2StatID$$aDBCoverage$$bPubMed Central$$d2025-11-06
000285915 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bNEUROTHERAPEUTICS : 2022$$d2025-11-06
000285915 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2025-04-16T07:50:47Z
000285915 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2025-04-16T07:50:47Z
000285915 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Anonymous peer review$$d2025-04-16T07:50:47Z
000285915 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2025-11-06
000285915 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2025-11-06
000285915 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2025-11-06
000285915 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2025-11-06
000285915 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2025-11-06
000285915 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2025-11-06
000285915 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bNEUROTHERAPEUTICS : 2022$$d2025-11-06
000285915 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$d2025-11-06
000285915 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2025-11-06
000285915 9201_ $$0I:(DE-2719)1011202$$kAG Boecker$$lPositron Emissions Tomography (PET)$$x0
000285915 9201_ $$0I:(DE-2719)1011001$$kClinical Research (Bonn)$$lClinical Research Coordination$$x1
000285915 9201_ $$0I:(DE-2719)5000075$$kAG Radbruch$$lClinical Neuroimaging$$x2
000285915 9201_ $$0I:(DE-2719)1011302$$kAG Wüllner$$lBiomarker Parkinson's Disease$$x3
000285915 9201_ $$0I:(DE-2719)1011101$$kPatient Studies (Bonn)$$lPatient Studies (Bonn)$$x4
000285915 980__ $$ajournal
000285915 980__ $$aEDITORS
000285915 980__ $$aVDBINPRINT
000285915 980__ $$aI:(DE-2719)1011202
000285915 980__ $$aI:(DE-2719)1011001
000285915 980__ $$aI:(DE-2719)5000075
000285915 980__ $$aI:(DE-2719)1011302
000285915 980__ $$aI:(DE-2719)1011101
000285915 980__ $$aUNRESTRICTED